product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human AMICA Fc Chimera Protein, CF
catalog :
3449-AM-050
quantity :
50 ug
price :
423 USD
more info or order :
citations: 1
Reference
Luissint A, Lutz P, Calderwood D, Couraud P, Bourdoulous S. JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation. J Cell Biol. 2008;183:1159-73 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3449-AM
SKU :
3449-AM-050
product name :
Recombinant Human AMICA Fc Chimera Protein, CF
Description :
The Recombinant Human AMICA Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human AMICA Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
AMICA/JAML
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
65-70 kDa, reducing conditions
theoretical molecular weight :
55.5 kDa (monomer)
gene symbol :
JAML
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of BT-20 human breast cancer cells. When 5 x 104 cells/well are added to rhAMICA/Fc Chimera coated plates (10 µg/mL, 100 µL/well), approximately 55%-75% will adhere after 1 hour at 37° C. Similar results were obtained using HeLa, A549, and T84 cell-lines. Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_694938
applications :
Bioactivity
source :
NS0-derived Recombinant Human AMICA Fc Chimera Protein
USD :
423 USD
alt names :
adhesion molecule, interacts with CXADR antigen 1, AMICA, AMICA1, CREA7-1, Gm638, JAML
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.