product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse ACE-2 Protein, CF
catalog :
3437-ZN-010
quantity :
10 ug
price :
432 USD
more info or order :
citations: 4
Reference
Martos Guillami N, Vergara A, Llorens Cebri xe0 C, Motto A, Mart xed nez D xed az I, Gon xe7 alves F, et al. SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice. Front Pharmacol. 2024;15:1415879 pubmed publisher
Riquelme C, Acuña M, Torrejón J, Rebolledo D, Cabrera D, Santos R, et al. ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis. PLoS ONE. 2014;9:e93449 pubmed publisher
Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature. 2012;487:477-81 pubmed publisher
Park S, Bivona B, Kobori H, Seth D, Chappell M, Lazartigues E, et al. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010;298:F37-48 pubmed publisher
product information
master code :
3437-ZN
SKU :
3437-ZN-010
product name :
Recombinant Mouse ACE-2 Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse ACE-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse ACE-2 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ACE-2
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and ZnCl2.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
110 kDa, reducing conditions
theoretical molecular weight :
85 kDa
gene symbol :
Ace2
details of functionality :
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007 ). The specific activity is 400 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse ACE-2 Protein Enzyme Activity
accessionNumbers :
NP_081562
applications :
Enzyme Activity
source long :
Chinese Hamster Ovary cell line, CHO-derived mouse ACE-2 protein Gln18-Thr740, with a C-terminal 10-His tag
source short :
CHO
USD :
432 USD
alt names :
ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.