Recombinant Mouse ACE-2 Protein, CF | R&D Systems 3437-ZN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ACE-2 Protein, CF

catalog :

3437-ZN-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Martos Guillami N, Vergara A, Llorens Cebri xe0 C, Motto A, Mart xed nez D xed az I, Gon xe7 alves F, et al. SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice. Front Pharmacol. 2024;15:1415879 pubmed publisher
Riquelme C, Acuña M, Torrejón J, Rebolledo D, Cabrera D, Santos R, et al. ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis. PLoS ONE. 2014;9:e93449 pubmed publisher
Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature. 2012;487:477-81 pubmed publisher
Park S, Bivona B, Kobori H, Seth D, Chappell M, Lazartigues E, et al. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010;298:F37-48 pubmed publisher

product information

master code :

3437-ZN

SKU :

3437-ZN-010

product name :

Recombinant Mouse ACE-2 Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse ACE-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse ACE-2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

ACE-2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and ZnCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

110 kDa, reducing conditions

theoretical molecular weight :

85 kDa

gene symbol :

Ace2

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007 ). The specific activity is 400 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse ACE-2 Protein Enzyme Activity

accessionNumbers :

NP_081562

applications :

Enzyme Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse ACE-2 protein Gln18-Thr740, with a C-terminal 10-His tag

source short :

CHO

USD :

432 USD

alt names :

ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage