Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein | R&D Systems 343-E2-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein

catalog :

343-E2-025

quantity :

25 ug

price :

283 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Dyer K, Rosenberg H. Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24). PLoS ONE. 2015;10:e0118887 pubmed publisher
Sturm E, Dyer K, Percopo C, Heinemann A, Rosenberg H. Chemotaxis of bone marrow derived eosinophils in vivo: a novel method to explore receptor-dependent trafficking in the mouse. Eur J Immunol. 2013;43:2217-28 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Ochkur S, Jacobsen E, Protheroe C, Biechele T, Pero R, McGarry M, et al. Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J Immunol. 2007;178:7879-89 pubmed
Beck L, Tancowny B, Brummet M, Asaki S, Curry S, Penno M, et al. Functional analysis of the chemokine receptor CCR3 on airway epithelial cells. J Immunol. 2006;177:3344-54 pubmed
Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D. CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands. J Immunol. 2006;176:5760-71 pubmed
Yamamoto H, Nagata M, Sakamoto Y. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1. Ann Allergy Asthma Immunol. 2005;94:292-300 pubmed
Wan Y, Jakway J, Qiu H, Shah H, Garlisi C, Tian F, et al. Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002;456:1-10 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

343-E2

SKU :

343-E2-025

product name :

Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein

Description :

The Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein has been validated for the following applications: Bioactivity.

target :

CCL24/Eotaxin-2/MPIF-2

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

10.6 kDa

gene symbol :

CCL24

details of functionality :

Measured by its ability to chemoattract Y3 rat myeloid cells transfected with human CCR3. The ED50 for this effect is 0.01-0.05 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR3. The ED50 for this effect is 0.01-0.05 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAB51135.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein

USD :

283 USD

alt names :

chemokine (C-C motif) ligand 24, Ckb-6, Eosinophil chemotactic protein 2, Eotaxin-2, member 24, MPIF2, MPIF-2, MPIF2Myeloid progenitor inhibitory factor 2, MPIF-2Small-inducible cytokine A24, SCYA24CK-beta-6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage