product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Activin RIIA Fc Chimera (CHO) Protein, CF
catalog :
340-RC2-100
quantity :
100 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Srole D, Jung G, Waring A, Nemeth E, Ganz T. Characterization of erythroferrone structural domains relevant to its iron-regulatory function. J Biol Chem. 2023;299:105374 pubmed publisher
product information
master code :
340-RC2
SKU :
340-RC2-100
product name :
Recombinant Human Activin RIIA Fc Chimera (CHO) Protein, CF
unit size :
100 ug
description :
The Recombinant Human Activin RIIA Fc Chimera (CHO) Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Activin RIIA Fc Chimera (CHO) Protein, CF has been validated for the following applications: Bioactivity.
target :
Activin RIIA
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
60-67 kDa, reducing conditions
theoretical molecular weight :
40 kDa (monomer)
gene symbol :
ACVR2A
details of functionality :
Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. etáal . (1991) Method Enzymol. 198 :340. Approximately 0.01-0.05 ╡g/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P27037
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human Activin RIIA protein Human Activin RIIA (Met1 - Pro134) Accession # P27037 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
CHO
USD :
456 USD
alt names :
activin A receptor, type II, activin A receptor, type IIA, Activin receptor type IIA, activin receptor type-2A, ActivinRIIA, ACTRII, ACTRIIA, ACVR2A, ACVR2ACTR-IIA, AVR2A, EC 2.7.11, EC 2.7.11.30
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.