Recombinant Human CCL22/MDC Protein | R&D Systems 336-MD-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL22/MDC Protein

catalog :

336-MD-025

quantity :

25 ug

price :

388 USD

more info or order :

R&D Systems product webpage

citations: 23

Reference
Jamal Jameel K, Gallert W, Yanik S, Panek S, Kronsbein J, Jungck D, et al. Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD. Int J Mol Sci. 2021;22: pubmed publisher
Kötting C, Hofmann L, Lotfi R, Engelhardt D, Laban S, Schuler P, et al. Immune-Stimulatory Effects of Curcumin on the Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
Okano J, Nakae Y, Nakagawa T, Katagi M, Terashima T, Nagakubo D, et al. A novel role for bone marrow-derived cells to recover damaged keratinocytes from radiation-induced injury. Sci Rep. 2021;11:5653 pubmed publisher
Fisher J, Zhang W, Balmert S, Aral A, Acharya A, Kulahci Y, et al. In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation. Sci Adv. 2020;6:eaax8429 pubmed publisher
Cameron A, Morrison V, Levin D, Mohan M, Forteath C, Beall C, et al. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status. Circ Res. 2016;119:652-65 pubmed publisher
Yu Q, Lou X, He Y. Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathway. PLoS ONE. 2015;10:e0120855 pubmed publisher
Nakagawa M, Schmitz R, Xiao W, Goldman C, Xu W, Yang Y, et al. Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. J Exp Med. 2014;211:2497-505 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Bonecchi R, Borroni E, Anselmo A, Doni A, Savino B, Mirolo M, et al. Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. Blood. 2008;112:493-503 pubmed publisher
Haas J, Schopp L, Storch Hagenlocher B, Fritzsching B, Jacobi C, Milkova L, et al. Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood. 2008;111:761-6 pubmed
Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
Hirahara K, Liu L, Clark R, Yamanaka K, Fuhlbrigge R, Kupper T. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol. 2006;177:4488-94 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Günther C, Bello Fernandez C, Kopp T, Kund J, Carballido Perrig N, Hinteregger S, et al. CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells. J Immunol. 2005;174:1723-8 pubmed
Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M. TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp Dermatol. 2004;13:551-7 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
Choi E, Jakubzick C, Carpenter K, Kunkel S, Evanoff H, Martinez F, et al. Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Am J Respir Crit Care Med. 2004;170:508-15 pubmed
Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, et al. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Immunology. 2004;112:274-89 pubmed
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product information

brand :

R&D Systems

master code :

336-MD

SKU :

336-MD-025

product name :

Recombinant Human CCL22/MDC Protein

description :

The Recombinant Human CCL22/MDC Protein from R&D Systems is derived from E. coli.

target :

CCL22/MDC

category :

Proteins and Enzymes

sizes available :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

8 kDa

gene symbol :

CCL22

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR4. The ED50 for this effect is 0.5-3 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

O00626.1

source :

E. coli-derived Recombinant Human CCL22/MDC Protein

USD :

388

USD 2023 :

388 USD

alt names :

A-152E5.1, ABCD-1, CC chemokine STCP-1, C-C motif chemokine 22, chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC, MDCStimulated T-cell chemotactic protein 1, MGC34554, SCYA22MDC(1-69), small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP-1, stimulated T cell chemotactic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage