Recombinant Human CCL5/Met-RANTES Protein, CF | R&D Systems 335-RM-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL5/Met-RANTES Protein, CF

catalog :

335-RM-025/CF

quantity :

25 ug

price :

294 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Arsiwala T, Vogt A, Barton A, Manolova V, Funk F, Fluhmann B, et al. Kupffer Cells and Blood Monocytes Orchestrate the Clearance of Iron-Carbohydrate Nanoparticles from Serum. Int J Mol Sci. 2022;23: pubmed publisher
Sun X, Chen Z. Cancer-associated fibroblast-derived CCL5 contributes to cisplatin resistance in A549 NSCLC cells partially through upregulation of lncRNA HOTAIR expression. Oncol Lett. 2021;22:696 pubmed publisher
Xu Y, Sun Y, Shen H, Dai Y, Liu H, Li R, et al. Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23. Nat Commun. 2018;9:3875 pubmed publisher
Hemalatha S, Sengodan S, Nadhan R, Dev J, Sushama R, Somasundaram V, et al. Brcal Defective Breast Cancer Cells Induce in vitro Transformation of Cancer Associated Fibroblasts (CAFs) to Metastasis Associated Fibroblasts (MAF). Sci Rep. 2018;8:13903 pubmed publisher
Chou S, Ajoy R, Changou C, Hsieh Y, Wang Y, Hoffer B. CCL5/RANTES contributes to hypothalamic insulin signaling for systemic insulin responsiveness through CCR5. Sci Rep. 2016;6:37659 pubmed publisher
Kanno S, Nishio H, Tanaka T, Motomura Y, Murata K, Ihara K, et al. Activation of an innate immune receptor, Nod1, accelerates atherogenesis in Apoe-/- mice. J Immunol. 2015;194:773-80 pubmed publisher
Liou J, Mao C, Ching Wah Sum D, Liu F, Lai Y, Li J, et al. Peritoneal administration of Met-RANTES attenuates inflammatory and nociceptive responses in a murine neuropathic pain model. J Pain. 2013;14:24-35 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

335-RM/CF

SKU :

335-RM-025/CF

product name :

Recombinant Human CCL5/Met-RANTES Protein, CF

Description :

The Recombinant Human CCL5/Met-RANTES Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human CCL5/Met-RANTES Protein, CF has been validated for the following applications: Bioactivity.

target :

CCL5/RANTES

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

7.8 kDa

gene symbol :

CCL5

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 0.02-0.1 µg/mL. Measured by its ability to chemoattract 2-day cultured human monocytes. Schall, T. et al . (1990) Nature 347 :669. The ED50 for this effect is 0.4-1.2 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P13501

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL5/Met-RANTES Protein

USD :

294 USD

alt names :

chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage