This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PSGL-1/CD162 Fc Chimera Protein, CF
catalog :
3345-PS
quantity :
50 ug
price :
339 USD
citations: 13
Reference
Malaker S, Pedram K, Ferracane M, Bensing B, Krishnan V, Pett C, et al. The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proc Natl Acad Sci U S A. 2019;116:7278-7287 pubmed publisher
Lavoie S, Dumas E, Vulesevic B, Neagoe P, White M, Sirois M. Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities. J Immunol. 2018;200:3801-3813 pubmed publisher
Lam F, Da Q, Guillory B, Cruz M. Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium. J Immunol. 2018;200:1718-1726 pubmed publisher
Pepin M, Mezouar S, Pegon J, Muczynski V, Adam F, Bianchini E, et al. Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity. Sci Rep. 2016;6:37953 pubmed publisher
Ku Z, Ye X, Shi J, Wang X, Liu Q, Huang Z. Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral Entry. J Virol. 2015;89:12084-95 pubmed publisher
Gutiérrez D, Pardo M, Montero D, Oñate A, Farfán M, Ruiz Pérez F, et al. TleA, a Tsh-like autotransporter identified in a human enterotoxigenic Escherichia coli strain. Infect Immun. 2015;83:1893-903 pubmed publisher
Ayala Lujan J, Vijayakumar V, Gong M, Smith R, Santiago A, Ruiz Perez F. Broad spectrum activity of a lectin-like bacterial serine protease family on human leukocytes. PLoS ONE. 2014;9:e107920 pubmed publisher
Riese S, Kuehne C, Tedder T, Hallmann R, Hohenester E, Buscher K. Heterotropic modulation of selectin affinity by allosteric antibodies affects leukocyte rolling. J Immunol. 2014;192:1862-9 pubmed publisher
Banks J, Herman C, Bailey R. Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. PLoS ONE. 2013;8:e78988 pubmed publisher
Deban L, Russo R, Sironi M, Moalli F, Scanziani M, Zambelli V, et al. Regulation of leukocyte recruitment by the long pentraxin PTX3. Nat Immunol. 2010;11:328-34 pubmed publisher
Wu Z, Ethen C, Larson S, Prather B, Jiang W. A versatile polyacrylamide gel electrophoresis based sulfotransferase assay. BMC Biotechnol. 2010;10:11 pubmed publisher
Baker H, Basu I, Chung M, Caradoc Davies T, Fraser J, Baker E. Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins. J Mol Biol. 2007;374:1298-308 pubmed
Simonis D, Fritzsche J, Alban S, Bendas G. Kinetic analysis of heparin and glucan sulfates binding to P-selectin and its impact on the general understanding of selectin inhibition. Biochemistry. 2007;46:6156-64 pubmed
product information
brand :
R&D Systems
master code :
3345-PS
SKU :
3345-PS-050
product name :
Recombinant Human PSGL-1/CD162 Fc Chimera Protein, CF
description :
The Recombinant Human PSGL-1/CD162 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human PSGL-1/CD162 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
PSGL-1/CD162
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Tris and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
100-150 kDa, reducing conditions
theoretical molecular weight :
52.6 kDa (monomer)
gene symbol :
SELPLG
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with P-Selectin. The ED50 for this effect is 0.04-0.32 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
3345-PS
accessionNumbers :
AAC50061
applications :
Bioactivity
source :
Chinese Hamster Ovary cell line, CHO-derived human PSGL-1/CD162 protein Human PSGL-1 (Gln42-Val295) Accession # AAC50061 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
2020 USD :
339
2021 USD :
339 USD
alt names :
CD162, CD162 antigen, P-selectin glycoprotein ligand 1, PSGL1, PSGL-1cutaneous lymphocyte-associated associated antigen, selectin P ligandCLA, SELPLG
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.