Recombinant Equine IL-1 beta/IL-1F2 Protein, CF | R&D Systems 3340-EL-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Equine IL-1 beta/IL-1F2 Protein, CF

catalog :

3340-EL-010/CF

quantity :

10 ug

price :

373 USD

citations: 11

Reference
Moyo N, Westcott D, Simmonds R, Steinbach F. Equine Arteritis Virus in Monocytic Cells Suppresses Differentiation and Function of Dendritic Cells. Viruses. 2023;15: pubmed publisher
Garbin L, McIlwraith C, Frisbie D. Use of allogeneic freeze-dried conditioned serum for the prevention of degradation in cartilage exposed to IL-1ß. BMC Vet Res. 2022;18:265 pubmed publisher
Jeremiasse B, Matta C, Fellows C, Boocock D, Smith J, Liddell S, et al. Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines. BMC Mol Cell Biol. 2020;21:47 pubmed publisher
Bundgaard L, Stensballe A, Elbæk K, Berg L. Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1β treatment. Stem Cell Res Ther. 2020;11:187 pubmed publisher
McGlinchey L, Agne G, Passler T, Cole R, Schumacher J. An Objective Assessment of the Effect of Anesthetizing the Median Nerve on Lameness Caused by Pain in the Cubital Joint. J Equine Vet Sci. 2019;75:9-13 pubmed publisher
Cassano J, Schnabel L, Goodale M, Fortier L. Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment. Stem Cell Res Ther. 2018;9:82 pubmed publisher
Castro Martins M, Peffers M, Lee K, Rubio Martínez L. Effects of stanozolol on normal and IL-1?-stimulated equine chondrocytes in vitro. BMC Vet Res. 2018;14:103 pubmed publisher
Singleton H, Graham S, Frossard J, Bodman Smith K, Steinbach F. Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10. Virology. 2018;517:199-207 pubmed publisher
Berghaus L, Giguere S, Bordin A, Cohen N. Effects of priming with cytokines on intracellular survival and replication of Rhodococcus equi in equine macrophages. Cytokine. 2018;102:7-11 pubmed publisher
Maumus M, Roussignol G, Toupet K, Penarier G, Bentz I, Teixeira S, et al. Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells. Front Immunol. 2016;7:392 pubmed
Ley C, Svala E, Nilton A, Lindahl A, Eloranta M, Ekman S, et al. Effects of high mobility group box protein-1, interleukin-1?, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures. Connect Tissue Res. 2011;52:290-300 pubmed publisher

product information

master code :

3340-EL/CF

SKU :

3340-EL-010/CF

product name :

Recombinant Equine IL-1 beta/IL-1F2 Protein, CF

unit size :

10 ug

description :

The Recombinant Equine IL-1 beta/IL-1F2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Equine IL-1 beta/IL-1F2 Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-1 beta/IL-1F2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Equine

theoretical molecular weight :

17 kDa

gene symbol :

IL1B

details of functionality :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. etáal . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etáal . (eds): IRL Press. 272. The ED50 for this effect is 5-30 pg/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q28386

applications :

Bioactivity

source long :

E. coli -derived equine IL-1 beta/IL-1F2 protein Ala116-Ala268 (Glu179Gly, Met188Thr, Thr194Ile, Ser245Lys and Arg256Gln)

source short :

E. coli

USD :

373 USD

alt names :

catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.