This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat FGF basic/FGF2/bFGF Protein
catalog :
3339-FB
quantity :
25 ug
price :
259 USD
citations: 28
Reference
Nakamura M, Nishida H, Yoshizaki K, Akiyoshi H, Hatoya S, Sugiura K, et al. Canine mesenchymal stromal cell-conditioned medium promotes survival and neurite outgrowth of neural stem cells. J Vet Med Sci. 2020;82:668-672 pubmed publisher
Liang X, Mao Q, Huang D, Tang J, Zheng J. Overexpression of cortistatin alleviates oxygen/glucose-deprivation-induced ER stress and prompts neural stem cell proliferation via SSTR2. Exp Mol Pathol. 2020;113:104351 pubmed publisher
Zanno A, Romer M, Fox L, Golden T, Jaeckle Santos L, Simmons R, et al. Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain. J Neurodev Disord. 2019;11:34 pubmed publisher
Park H, Han M, Choi H, Lee Y, Kim J, Cheong J, et al. Mitochondria damaged by Oxygen Glucose Deprivation can be Restored through Activation of the PI3K/Akt Pathway and Inhibition of Calcium Influx by Amlodipine Camsylate. Sci Rep. 2019;9:15717 pubmed publisher
Lee E, Kim S, Kim C, Pagire S, Pagire H, Chung H, et al. Dopamine neuron induction and the neuroprotective effects of thyroid hormone derivatives. Sci Rep. 2019;9:13659 pubmed publisher
Sankavaram S, Hakim R, Covacu R, Frostell A, Neumann S, Svensson M, et al. Adult Neural Progenitor Cells Transplanted into Spinal Cord Injury Differentiate into Oligodendrocytes, Enhance Myelination, and Contribute to Recovery. Stem Cell Reports. 2019;12:950-966 pubmed publisher
Zhang W, Li X, Sun S, Zhang X. Implantation of engineered conduction tissue in the rat heart. Mol Med Rep. 2019;19:2687-2697 pubmed publisher
Sun X, Zhu Y, Yin H, Guo Z, Xu F, Xiao B, et al. Differentiation of adipose-derived stem cells into Schwann cell-like cells through intermittent induction: potential advantage of cellular transient memory function. Stem Cell Res Ther. 2018;9:133 pubmed publisher
Robinson J, Egbert J, Davydova J, Schmidt H, Jaffe L, Potter L. Dephosphorylation is the mechanism of fibroblast growth factor inhibition of guanylyl cyclase-B. Cell Signal. 2017;40:222-229 pubmed publisher
Karkera J, Cardona G, Bell K, Gaffney D, Portale J, Santiago Walker A, et al. Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib. Mol Cancer Ther. 2017;16:1717-1726 pubmed publisher
Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, et al. Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep. 2017;7:40295 pubmed publisher
Vitacolonna M, Belharazem D, Hohenberger P, Roessner E. In-vivo quantification of the revascularization of a human acellular dermis seeded with EPCs and MSCs in co-culture with fibroblasts and pericytes in the dorsal chamber model in pre-irradiated tissue. Cell Tissue Bank. 2017;18:27-43 pubmed publisher
Kang M, Park S, Han J. Hippocalcin Is Required for Astrocytic Differentiation through Activation of Stat3 in Hippocampal Neural Precursor Cells. Front Mol Neurosci. 2016;9:110 pubmed
Yu S, Yao S, Wen Y, Wang Y, Wang H, Xu Q. Angiogenic microspheres promote neural regeneration and motor function recovery after spinal cord injury in rats. Sci Rep. 2016;6:33428 pubmed publisher
He X, Kim M, Kim S, Yi S, Rhee Y, Kim T, et al. Vitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control manner. Stem Cells. 2015;33:1320-32 pubmed publisher
Xu W, Sun Y, Zhang J, Xu K, Pan L, He L, et al. Perivascular-derived stem cells with neural crest characteristics are involved in tendon repair. Stem Cells Dev. 2015;24:857-68 pubmed publisher
Covacu R, Pérez Estrada C, Arvidsson L, Svensson M, Brundin L. Change of fate commitment in adult neural progenitor cells subjected to chronic inflammation. J Neurosci. 2014;34:11571-82 pubmed publisher
Romariz S, Paiva D, Valente M, Barnabé G, Frussa Filho R, Barbosa Silva R, et al. Long-lasting anxiolytic effect of neural precursor cells freshly prepared but not neurosphere-derived cell transplantation in newborn rats. BMC Neurosci. 2014;15:94 pubmed publisher
Kandasamy M, Lehner B, Kraus S, Sander P, Marschallinger J, Rivera F, et al. TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons. J Cell Mol Med. 2014;18:1444-59 pubmed publisher
Reed D, Foldes G, Gatheral T, Paschalaki K, Lendvai Z, Bagyura Z, et al. Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors. PLoS ONE. 2014;9:e91119 pubmed publisher
Matsushita M, Kitoh H, Ohkawara B, Mishima K, Kaneko H, Ito M, et al. Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia. PLoS ONE. 2013;8:e81569 pubmed publisher
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Qi L, Li N, Huang R, Song Q, Wang L, Zhang Q, et al. The effects of topographical patterns and sizes on neural stem cell behavior. PLoS ONE. 2013;8:e59022 pubmed publisher
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product information
brand :
R&D Systems
master code :
3339-FB
SKU :
3339-FB-025
product name :
Recombinant Rat FGF basic/FGF2/bFGF Protein
description :
The Recombinant Rat FGF basic/FGF2/bFGF Protein from R&D Systems is derived from E. coli. The Recombinant Rat FGF basic/FGF2/bFGF Protein has been validated for the following applications: Bioactivity.
target :
FGF basic/FGF2/bFGF
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Rat
theoretical molecular weight :
16.2 kDa
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.3-1.8 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
3339-FB
accessionNumbers :
P13109
applications :
Bioactivity
source :
E. coli -derived rat FGF basic/FGF2/bFGF protein Ala11-Ser154
2020 USD :
259
2021 USD :
259 USD
alt names :
Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.