Recombinant Human CXADR Fc Chimera Protein, CF | R&D Systems 3336-CX-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CXADR Fc Chimera Protein, CF

catalog :

3336-CX-050

quantity :

50 ug

price :

432 USD

citations: 6

Reference
Jayabal P, Zhou F, Ma X, Bondra K, Blackman B, Weintraub S, et al. Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma. Cell Rep. 2023;42:112103 pubmed publisher
Eschweiler S, Wang A, Ram xed rez Su xe1 stegui C, von Witzleben A, Li Y, Chee S, et al. JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells. Cell Rep. 2023;42:112040 pubmed publisher
Rajan A, Palm E, Trulsson F, Mundigl S, Becker M, Persson B, et al. Heparan Sulfate Is a Cellular Receptor for Enteric Human Adenoviruses. Viruses. 2021;13: pubmed publisher
Baker A, Greenshields Watson A, Coughlan L, Davies J, Uusi Kerttula H, Cole D, et al. Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions. Nat Commun. 2019;10:741 pubmed publisher
Lenman A, Liaci A, Liu Y, Årdahl C, Rajan A, Nilsson E, et al. Human adenovirus 52 uses sialic acid-containing glycoproteins and the coxsackie and adenovirus receptor for binding to target cells. PLoS Pathog. 2015;11:e1004657 pubmed publisher
Ivie S, Fennessey C, Sheng J, Rubin D, McClain M. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ?-toxin. PLoS ONE. 2011;6:e17787 pubmed publisher

product information

master code :

3336-CX

SKU :

3336-CX-050

product name :

Recombinant Human CXADR Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human CXADR Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CXADR Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CXADR

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

60-65 kDa, reducing conditions

theoretical molecular weight :

50.6 kDa (monomer)

gene symbol :

CXADR

details of functionality :

Measured by its binding ability in a functional ELISA. Recombinant Human CXADR Fc Chimera (Catalog # 3336-CX) binds Recombinant Human AMICA/JAML Fc Chimera (Catalog # 3449-AM ) with an ED50 of 2.50-25.0 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P78310

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human CXADR protein Human CXADR (Leu20 - Gly237) Accession # P78310 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

CAR10Coxsackievirus B-adenovirus receptor, CAR4/6, coxsackie virus and adenovirus receptor, coxsackie virus B receptor, coxsackievirus and adenovirus receptor, CVB3 binding protein, CVB3 BP, CVB3-binding protein, hCAR, HCVADR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.