Recombinant Human CXCL6/GCP-2 Protein, CF | R&D Systems 333-GC-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CXCL6/GCP-2 Protein, CF

catalog :

333-GC-025/CF

quantity :

25 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Ma J, Sun X, Su H, Chen Q, Guo T, Li Y, et al. Fibroblast-derived CXCL12/SDF-1Î± promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer. World J Gastroenterol. 2017;23:5167-5178 pubmed publisher
Laarman A, Mijnheer G, Mootz J, van Rooijen W, Ruyken M, Malone C, et al. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J. 2012;31:3607-19 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Begley L, Kasina S, MacDonald J, Macoska J. The inflammatory microenvironment of the aging prostate facilitates cellular proliferation and hypertrophy. Cytokine. 2008;43:194-9 pubmed publisher
Nguyen A, Stebbins E, Henson M, O Young G, Choi S, Quon D, et al. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation. Exp Cell Res. 2006;312:1909-23 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

333-GC/CF

SKU :

333-GC-025/CF

product name :

Recombinant Human CXCL6/GCP-2 Protein, CF

Description :

The Recombinant Human CXCL6/GCP-2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human CXCL6/GCP-2 Protein, CF has been validated for the following applications: Bioactivity.

target :

CXCL6/GCP-2

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

8 kDa

gene symbol :

CXCL6

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 3-15 ng/mL. Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al . (1987) J. Immunol. 139 :3474. The ED50 for this effect is 0.5-1.5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P80162

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CXCL6/GCP-2 Protein

USD :

396 USD

alt names :

chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2), Chemokine alpha 3, CKA-3Granulocyte chemotactic protein 2, GCP-2, GCP2member 6 (granulocytechemotactic protein 2), GCP-2Small-inducible cytokine B6, Small inducible cytokine subfamily B (Cys-X-Cys), member b

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage