product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD117/c-kit Protein, CF
catalog :
332-SR-050/CF
quantity :
50 ug
price :
458 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Tilayov T, Hingaly T, Greenshpan Y, Cohen S, Akabayov B, Gazit R, et al. Engineering Stem Cell Factor Ligands with Different c-Kit Agonistic Potencies. Molecules. 2020;25: pubmed publisher
Levesque J, Hendy J, Winkler I, Takamatsu Y, Simmons P. Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells. Exp Hematol. 2003;31:109-17 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
332-SR/CF
SKU :
332-SR-050/CF
product name :
Recombinant Human CD117/c-kit Protein, CF
Description :
The Recombinant Human CD117/c-kit Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human CD117/c-kit Protein, CF has been validated for the following applications: Bioactivity.
target :
CD117/c-kit
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
59-63 kDa, reducing conditions
theoretical molecular weight :
55.7 kDa
gene symbol :
KIT
details of functionality :
Measured by its ability to inhibit SCF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 2-6 µg/mL in the presence of 8 ng/mL of Recombinant Human SCF.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P10721
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Human CD117/c-kit Protein
USD :
458 USD
alt names :
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.