Recombinant Human M-CSF R/CD115 Fc Chimera Protein | R&D Systems 329-MR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human M-CSF R/CD115 Fc Chimera Protein

catalog :

329-MR

quantity :

100 ug

price :

369 USD

citations: 6

Reference
Rao P, Ande A, Sinha N, Kumar A, Kumar S. Effects of Cigarette Smoke Condensate on Oxidative Stress, Apoptotic Cell Death, and HIV Replication in Human Monocytic Cells. PLoS ONE. 2016;11:e0155791 pubmed publisher
Matsuda K, Chen C, Whitted S, Chertova E, Roser D, Wu F, et al. Enhanced antagonism of BST-2 by a neurovirulent SIV envelope. J Clin Invest. 2016;126:2295-307 pubmed publisher
Pourcet B, Gage M, LeÃ³n T, Waddington K, Pello O, Steffensen K, et al. The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms. Sci Rep. 2016;6:25481 pubmed publisher
Ussher J, van Wilgenburg B, Hannaway R, Ruustal K, Phalora P, Kurioka A, et al. TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAITÂ cells. Eur J Immunol. 2016;46:1600-14 pubmed publisher
Haka A, Barbosa Lorenzi V, Lee H, Falcone D, Hudis C, Dannenberg A, et al. Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation. J Lipid Res. 2016;57:980-92 pubmed publisher
Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, et al. Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma. Nat Med. 2010;16:571-9, 1p following 579 pubmed publisher

product information

brand :

R&D Systems

master code :

329-MR

SKU :

329-MR-100

product name :

Recombinant Human M-CSF R/CD115 Fc Chimera Protein

description :

The Recombinant Human M-CSF R/CD115 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human M-CSF R/CD115 Fc Chimera Protein has been validated for the following applications: Bioactivity.

target :

M-CSFR/CD115

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

150 kDa, reducing conditions

theoretical molecular weight :

81 kDa (monomer)

gene symbol :

CSF1R

details of functionality :

Measured by its ability to inhibit the M-CSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. Halenbeck, R. et al . (1989) Biotechnology 7 :710. The ED50 for this effect is 0.004-0.012 µg/mL in the presence of 1 ng/mL of Recombinant Human M-CSF (Catalog # 216-MC ).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

329-MR

accessionNumbers :

CAA27300

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human M-CSF R/CD115 protein Human M-CSF R (Ile20-Glu512) Accession # CAA27300 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus

2020 USD :

369

2021 USD :

369 USD

alt names :

CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, CSF1R, CSF-1-R, CSFR, EC 2.7.10.1, FMS proto-oncogene, FMSFIM2, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, MCSFR, M-CSFR, Proto-oncogene c-Fms

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.