Recombinant Human CCL13/MCP-4 Protein | R&D Systems 327-P4-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL13/MCP-4 Protein

catalog :

327-P4-025

quantity :

25 ug

price :

273 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
Yamamoto H, Nagata M, Sakamoto Y. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1. Ann Allergy Asthma Immunol. 2005;94:292-300 pubmed
Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
Wan Y, Jakway J, Qiu H, Shah H, Garlisi C, Tian F, et al. Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002;456:1-10 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

327-P4

SKU :

327-P4-025

product name :

Recombinant Human CCL13/MCP-4 Protein

Description :

The Recombinant Human CCL13/MCP-4 Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL13/MCP-4 Protein has been validated for the following applications: Bioactivity.

target :

CCL13/MCP-4

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

8.6 kDa

gene symbol :

CCL13

details of functionality :

Measured by its ability to chemoattract 2-day cultured human monocytes. Matsushima, K. et al . (1989) J. Exp. Med. 169 :1485. The ED50 for this effect is 0.02-0.06 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR2A. The ED50 for this effect is 0.5-2 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q99616.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL13/MCP-4 Protein

USD :

273 USD

alt names :

C-C motif chemokine 13, chemokine (C-C motif) ligand 13, CKb10, MCP4, MCP-4, MCP-4Monocyte chemoattractant protein 4, MGC17134, NCC-1Monocyte chemotactic protein 4, NCC1Small-inducible cytokine A13, new CC chemokine 1, SCYA13CK-beta-10, SCYL1, small inducible cytokine subfamily A (Cys-Cys), member 13

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage