This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Fas/TNFRSF6/CD95 Fc Chimera Protein
catalog :
326-FS
quantity :
50 ug
price :
355 USD
citations: 3
| Reference |
|---|
Juang S, Wei S, Hung Y, Hsu C, Yang D, Liu K, et al. IFN-beta induces caspase-mediated apoptosis by disrupting mitochondria in human advanced stage colon cancer cell lines. J Interferon Cytokine Res. 2004;24:231-43 pubmed
|
Ryon J, Moss W, Monze M, Griffin D. Functional and phenotypic changes in circulating lymphocytes from hospitalized zambian children with measles. Clin Diagn Lab Immunol. 2002;9:994-1003 pubmed
|
product information
brand :
R&D Systems
master code :
326-FS
SKU :
326-FS-050
product name :
Recombinant Human Fas/TNFRSF6/CD95 Fc Chimera Protein
description :
The Recombinant Human Fas/TNFRSF6/CD95 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human Fas/TNFRSF6/CD95 Fc Chimera Protein has been validated for the following applications: Bioactivity.
target :
Fas/TNFRSF6/CD95
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
45 kDa (monomer)
gene symbol :
FAS
details of functionality :
Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. et al . (1994) Science 263 :1759. The ED50 for this effect is 0.01-0.04 µg/mL in the presence of 2 ng/mL recombinant human Fas Ligand.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
326-FS
accessionNumbers :
Q5T9P3
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human Fas/TNFRSF6/CD95 protein Human Fas (Arg17-Asn173) Accession # Q5T9P3 IEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
extended description :
New rhFas! HEK293 expressed; ~2 fold better activity; Lower endotoxin specification; No His tag!
2020 USD :
355
2021 USD :
355 USD
product details :
New rhFas! HEK293 expressed; ~2 fold better activity; Lower endotoxin specification; No His tag!
alt names :
Apo-1, Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1, APT1FASTM, CD95, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
questions and comments