product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Podoplanin Fc Chimera Protein, CF
catalog :
3244-PL-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Xie Z, Shao B, Hoover C, McDaniel M, Song J, Jiang M, et al. Monocyte upregulation of podoplanin during early sepsis induces complement inhibitor release to protect liver function. JCI Insight. 2020;5: pubmed publisher
Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed publisher
Boulaftali Y, Hess P, Getz T, Cholka A, Stolla M, Mackman N, et al. Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest. 2013;123:908-16 pubmed publisher
product information
master code :
3244-PL
SKU :
3244-PL-050
product name :
Recombinant Mouse Podoplanin Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse Podoplanin Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Podoplanin Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Podoplanin
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
45-70 kDa, reducing conditions
theoretical molecular weight :
19.0 kDa (monomer)
gene symbol :
Pdpn
details of functionality :
Measured by its binding ability in a functional ELISA. When 0.5 ╡g/mL of rmPodoplanin/Fc is immobilized onto a Goat Anti-Mouse IgG Fc chimera (R D Systems, Catalog # G-202-C) coated plate, the concentration of rhCLEC-2 that produces 50% of the optimal binding response is found to be approximately 0.3-1.8 nM.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q62011
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse Podoplanin protein Mouse Podoplanin (Gln21-Lys133) Accession # Q62011 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
36-KD, aggrus, Gp36, Gp38, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), OTS 8, OTS8, PA2.26 antigen, PDPN, podoplanin, RANDAM-2, T1A, T1A-2, T1-alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.