Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF | R&D Systems 3237-S3-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF

catalog :

3237-S3-025

quantity :

25 ug

price :

598 USD

citations: 8

Reference
Murphy K, Duncan B, Sperringer J, Zhang E, Haberman V, Wyatt E, et al. Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex. bioRxiv. 2023;: pubmed publisher
Mohan V, Wade S, Sullivan C, Kasten M, Sweetman C, Stewart R, et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci. 2019;39:6233-6250 pubmed publisher
Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E. In vivo topology converts competition for cell-matrix adhesion into directional migration. Nat Commun. 2019;10:1518 pubmed publisher
Reuer T, Schneider A, Cakir B, Bühler A, Walz J, Lapp T, et al. Semaphorin 3F Modulates Corneal Lymphangiogenesis and Promotes Corneal Graft Survival. Invest Ophthalmol Vis Sci. 2018;59:5277-5284 pubmed publisher
Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub R. Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis. Life Sci. 2017;168:47-53 pubmed publisher
Demyanenko G, Mohan V, Zhang X, Brennaman L, Dharbal K, Tran T, et al. Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling. J Neurosci. 2014;34:11274-87 pubmed publisher
Mendes da Cruz D, Brignier A, Asnafi V, Baleydier F, Messias C, Lepelletier Y, et al. Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. PLoS ONE. 2014;9:e103405 pubmed publisher
Naska S, Lin D, Miller F, Kaplan D. p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse. Mol Cell Neurosci. 2010;45:108-20 pubmed publisher

product information

master code :

3237-S3

SKU :

3237-S3-025

product name :

Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF

unit size :

25 ug

description :

The Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF from R&D Systems is derived from NS0. The Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF has been validated for the following applications: Bioactivity.

target :

Semaphorin 3F

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Citric Acid and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

110-122 kDa, reducing conditions

theoretical molecular weight :

111.6 kDa (monomer)

gene symbol :

Sema3f

details of functionality :

Measured by its ability to inhibit proliferation of the A549 human lung carcinoma cells. The ED50 for this effect is 40-120 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O88632

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Semaphorin 3F protein Mouse Semaphorin 3F Ala19-Pro775 (Arg583Ala and Arg586Ala) Accession # O88632 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

598 USD

alt names :

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F, sema III/F, sema IV, Sema3F, SEMA4, SEMA-IV, SEMAK, semaphorin III/F, semaphorin IV

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.