product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF
catalog :
3237-S3-025
quantity :
25 ug
price :
580 USD
more info or order :
citations: 8
Reference
Murphy K, Duncan B, Sperringer J, Zhang E, Haberman V, Wyatt E, et al. Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex. bioRxiv. 2023;: pubmed publisher
Mohan V, Wade S, Sullivan C, Kasten M, Sweetman C, Stewart R, et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci. 2019;39:6233-6250 pubmed publisher
Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E. In vivo topology converts competition for cell-matrix adhesion into directional migration. Nat Commun. 2019;10:1518 pubmed publisher
Reuer T, Schneider A, Cakir B, Bühler A, Walz J, Lapp T, et al. Semaphorin 3F Modulates Corneal Lymphangiogenesis and Promotes Corneal Graft Survival. Invest Ophthalmol Vis Sci. 2018;59:5277-5284 pubmed publisher
Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub R. Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis. Life Sci. 2017;168:47-53 pubmed publisher
Demyanenko G, Mohan V, Zhang X, Brennaman L, Dharbal K, Tran T, et al. Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling. J Neurosci. 2014;34:11274-87 pubmed publisher
Mendes da Cruz D, Brignier A, Asnafi V, Baleydier F, Messias C, Lepelletier Y, et al. Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. PLoS ONE. 2014;9:e103405 pubmed publisher
Naska S, Lin D, Miller F, Kaplan D. p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse. Mol Cell Neurosci. 2010;45:108-20 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3237-S3
SKU :
3237-S3-025
product name :
Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF
Description :
The Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF from R&D Systems is derived from NS0. The Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated), CF has been validated for the following applications: Bioactivity.
target :
Semaphorin 3F
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Citric Acid and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
110-122 kDa, reducing conditions
theoretical molecular weight :
111.6 kDa (monomer)
gene symbol :
Sema3f
details of functionality :
Measured by its ability to inhibit proliferation of the A549 human lung carcinoma cells. The ED50 for this effect is 40-120 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
O88632
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Semaphorin 3F Fc Chimera (Truncated)
USD :
580 USD
alt names :
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F, sema III/F, sema IV, Sema3F, SEMA4, SEMA-IV, SEMAK, semaphorin III/F, semaphorin IV
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.