Recombinant Human CCL11/Eotaxin Protein | R&D Systems 320-EO-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL11/Eotaxin Protein

catalog :

320-EO-020

quantity :

20 ug (also 100 ug)

price :

340 USD

more info or order :

R&D Systems product webpage

citations: 28

Reference
Déry L, Charest G, Guérin B, Akbari M, Fortin D. Chemoattraction of Neoplastic Glial Cells with CXCL10, CCL2 and CCL11 as a Paradigm for a Promising Therapeutic Approach for Primary Brain Tumors. Int J Mol Sci. 2021;22: pubmed publisher
Germic N, Fettrelet T, Stojkov D, Hosseini A, Horn M, Karaulov A, et al. The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells. 2021;10: pubmed publisher
de Ruiter K, van Staveren S, Hilvering B, Knol E, Vrisekoop N, Koenderman L, et al. A field-applicable method for flow cytometric analysis of granulocyte activation: Cryopreservation of fixed granulocytes. Cytometry A. 2018;93:540-547 pubmed publisher
Malard B, Florens N, Lambert C, Juillard L. Adsorption as a Contributor for Inflammatory Mediators Removal by Different Hemofiltration Membranes: A Pilot Study. Artif Organs. 2017;41:545-555 pubmed publisher
Akuthota P, Carmo L, Bonjour K, Murphy R, Silva T, Gamalier J, et al. Extracellular Microvesicle Production by Human Eosinophils Activated by "Inflammatory" Stimuli. Front Cell Dev Biol. 2016;4:117 pubmed
Baldissera L, Squebola Cola D, Calixto M, Lima Barbosa A, Rennó A, Anhê G, et al. The soluble guanylyl cyclase activator BAY 60-2770 inhibits murine allergic airways inflammation and human eosinophil chemotaxis. Pulm Pharmacol Ther. 2016;41:86-95 pubmed publisher
Cameron A, Morrison V, Levin D, Mohan M, Forteath C, Beall C, et al. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status. Circ Res. 2016;119:652-65 pubmed publisher
Tahapary D, de Ruiter K, Martin I, van Lieshout L, Guigas B, Soewondo P, et al. Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia. BMC Infect Dis. 2015;15:133 pubmed publisher
Konno Y, Ueki S, Takeda M, Kobayashi Y, Tamaki M, Moritoki Y, et al. Functional analysis of free fatty acid receptor GPR120 in human eosinophils: implications in metabolic homeostasis. PLoS ONE. 2015;10:e0120386 pubmed publisher
Morshed M, Hlushchuk R, Simon D, Walls A, Obata Ninomiya K, Karasuyama H, et al. NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol. 2014;192:5314-23 pubmed publisher
Zhu F, Liu P, Li J, Zhang Y. Eotaxin-1 promotes prostate cancer cell invasion via activation of the CCR3-ERK pathway and upregulation of MMP-3 expression. Oncol Rep. 2014;31:2049-54 pubmed publisher
Melo R, Paganoti G, Dvorak A, Weller P. The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography. PLoS ONE. 2013;8:e59578 pubmed publisher
El Shazly A, Begon D, Kustermans G, Arafa M, Dortu E, Henket M, et al. Novel association between vasoactive intestinal peptide and CRTH2 receptor in recruiting eosinophils: a possible biochemical mechanism for allergic eosinophilic inflammation of the airways. J Biol Chem. 2013;288:1374-84 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Villeda S, Luo J, Mosher K, Zou B, Britschgi M, Bieri G, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011;477:90-4 pubmed publisher
Suzukawa M, Nagase H, Ogahara I, Han K, Tashimo H, Shibui A, et al. Leptin enhances survival and induces migration, degranulation, and cytokine synthesis of human basophils. J Immunol. 2011;186:5254-60 pubmed publisher
Puxeddu I, Berkman N, Ribatti D, Bader R, Haitchi H, Davies D, et al. Osteopontin is expressed and functional in human eosinophils. Allergy. 2010;65:168-74 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed publisher
Bonecchi R, Borroni E, Anselmo A, Doni A, Savino B, Mirolo M, et al. Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. Blood. 2008;112:493-503 pubmed publisher
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Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
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product information

brand :

R&D Systems

master code :

320-EO

SKU :

320-EO-020

product name :

Recombinant Human CCL11/Eotaxin Protein

description :

The Recombinant Human CCL11/Eotaxin Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL11/Eotaxin Protein has been validated for the following applications: Bioactivity.

target :

CCL11/Eotaxin

category :

Proteins and Enzymes

sizes available :

20 ug (also 100 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

8.4 kDa

gene symbol :

CCL11

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR3. The ED50 for this effect is 1-5 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q6I9T4

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL11/Eotaxin Protein

USD :

334

USD 2023 :

340 USD

alt names :

C-C motif chemokine 11, chemokine (C-C motif) ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA11Small-inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage