Recombinant Human Myeloperoxidase Protein, CF | R&D Systems 3174-MP-250 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Myeloperoxidase Protein, CF

catalog :

3174-MP-250

quantity :

250 ug

price :

265 USD

citations: 9

Reference
Cartwright I, Zhou L, Koch S, Welch N, Zakharov D, Callahan R, et al. Chlorination of epithelial tight junction proteins by neutrophil myeloperoxidase promotes barrier dysfunction and mucosal inflammation. JCI Insight. 2024;9: pubmed publisher
Archer M, Dasari P, Walsh D, Britt K, Evdokiou A, Ingman W. Immune Regulation of Mammary Fibroblasts and the Impact of Mammographic Density. J Clin Med. 2022;11: pubmed publisher
Rozelle A, Cheun Y, Vilas C, Koag M, Lee S. DNA interstrand cross-links induced by the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine. Nat Commun. 2021;12:1897 pubmed publisher
Tóth E, Varga M, Takó M, Homa M, Jáger O, Hermesz E, et al. Response of Human Neutrophil Granulocytes to the Hyphae of the Emerging Fungal Pathogen Curvularia lunata. Pathogens. 2020;9: pubmed publisher
Ploscariu N, de Jong N, Van Kessel K, Van Strijp J, Geisbrecht B. Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini. Arch Biochem Biophys. 2018;645:1-11 pubmed publisher
de Jong N, Ploscariu N, Ramyar K, Garcia B, Herrera A, Prakash O, et al. A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN). J Biol Chem. 2018;293:2260-2271 pubmed publisher
de Jong N, Ramyar K, Guerra F, Nijland R, Fevre C, Voyich J, et al. Immune evasion by a staphylococcal inhibitor of myeloperoxidase. Proc Natl Acad Sci U S A. 2017;114:9439-9444 pubmed publisher
Saha P, Yeoh B, Singh R, Chandrasekar B, Vemula P, Haribabu B, et al. Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme Peroxidases. PLoS ONE. 2016;11:e0156811 pubmed publisher
Huang S, Feng C, Hung H, Chakraborty C, Chen C, Chen W, et al. A novel zebrafish model to provide mechanistic insights into the inflammatory events in carrageenan-induced abdominal edema. PLoS ONE. 2014;9:e104414 pubmed publisher

product information

master code :

3174-MP

SKU :

3174-MP-250

product name :

Recombinant Human Myeloperoxidase Protein, CF

unit size :

250 ug

description :

The Recombinant Human Myeloperoxidase Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Myeloperoxidase Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Myeloperoxidase/MPO

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

74-106 kDa, under reducing conditions.

theoretical molecular weight :

80 kDa

gene symbol :

MPO

details of functionality :

Measured by its ability to oxidize guaiacol in the presence of hydrogen peroxide. Capeillere-Blandin, C. (1998) Biochem J. 336 :395. The specific activity is 50,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P05164

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Myeloperoxidase/MPO protein Ala49-Ser745, with a C-terminal 10-His tag

source short :

NS0

USD :

265 USD

alt names :

EC 1.11.1, EC 1.11.1.7, MPO, myeloperoxidase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.