Recombinant Human ROBO2 Fc Chimera Protein, CF | R&D Systems 3147-RB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human ROBO2 Fc Chimera Protein, CF

catalog :

3147-RB-050

quantity :

50 ug

price :

468 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Gonçalves A, Correia Pinto J, Nogueira Silva C. ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia. Respir Res. 2020;21:302 pubmed publisher
Greaves E, Collins F, Esnal Zufiaurre A, Giakoumelou S, Horne A, Saunders P. Estrogen receptor (ER) agonists differentially regulate neuroangiogenesis in peritoneal endometriosis via the repellent factor SLIT3. Endocrinology. 2014;155:4015-26 pubmed publisher
Ricaño Cornejo I, Altick A, García Peña C, Nural H, Echevarria D, Miquelajauregui A, et al. Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain. J Neurosci Res. 2011;89:1531-41 pubmed publisher

product information

master code :

3147-RB

SKU :

3147-RB-050

product name :

Recombinant Human ROBO2 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human ROBO2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ROBO2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

ROBO2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

146-160 kDa, reducing conditions

theoretical molecular weight :

120 kDa (monomer)

gene symbol :

ROBO2

details of functionality :

Measured by its binding ability in a functional ELISA. Biotinylated recombinant mouse Slit-3 immobilized on a streptavidin-coated plate at 1 ╡g/mL can bind Recombinant Human ROBO2 Fc Chimera with an apparent Kd 10 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001276969

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human ROBO2 protein Human ROBO2 (Ser22-Pro863) Accession # NP_001276969 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

468 USD

alt names :

Drosophila) homolog 2, roundabout, axon guidance receptor, homolog 2 (Drosophila), SAX3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage