Recombinant Rat CCL2/JE/MCP-1 Protein | R&D Systems 3144-JE-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat CCL2/JE/MCP-1 Protein

catalog :

3144-JE-025

quantity :

25 ug

price :

420 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Tsushima H, Yamada K. Effects of adipokine administration to the hypothalamic preoptic area on body temperature in rats. J Pharmacol Sci. 2020;144:61-68 pubmed publisher
Ding X, Yang W, Ren Q, Hu J, Yang S, Han W, et al. Serum IgG-induced microglial activation enhances neuronal cytolysis via the NO/sGC/PKG pathway in children with opsoclonus-myoclonus syndrome and neuroblastoma. J Neuroinflammation. 2020;17:190 pubmed publisher
Lee H, Liu S, Lin C, Lee S, Hsu C, Sytwu H, et al. A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics. 2017;7:855-875 pubmed publisher
Strazielle N, Creidy R, Malcus C, Boucraut J, Ghersi Egea J. T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium. PLoS ONE. 2016;11:e0150945 pubmed publisher
Huang C, Chen Y, Li A, Lu J, Wang H. Minocycline, a microglial inhibitor, blocks spinal CCL2-induced heat hyperalgesia and augmentation of glutamatergic transmission in substantia gelatinosa neurons. J Neuroinflammation. 2014;11:7 pubmed publisher
Vomaske J, Denton M, Kreklywich C, Andoh T, Osborn J, Chen D, et al. Cytomegalovirus CC chemokine promotes immune cell migration. J Virol. 2012;86:11833-44 pubmed publisher
Bhangoo S, Ren D, Miller R, Chan D, Ripsch M, Weiss C, et al. CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy. Brain Behav Immun. 2007;21:581-91 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3144-JE

SKU :

3144-JE-025

product name :

Recombinant Rat CCL2/JE/MCP-1 Protein

Description :

The Recombinant Rat CCL2/JE/MCP-1 Protein from R&D Systems is derived from NS0. The Recombinant Rat CCL2/JE/MCP-1 Protein has been validated for the following applications: Bioactivity.

target :

CCL2/JE/MCP-1

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose and with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Rat

observed molecular weight :

25-35 kDa, reducing conditions

theoretical molecular weight :

14 kDa

gene symbol :

Ccl2

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR2A. The ED50 for this effect is 30-150 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P14844

applications :

Bioactivity

source :

NS0-derived Recombinant Rat CCL2/JE/MCP-1 Protein

USD :

420 USD

alt names :

C-C motif chemokine ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MCAF, Mcp1, MCP-1, SCYA2, SMC-CF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage