Recombinant Human MEPE/OF45 Protein, CF | R&D Systems 3140-ME-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MEPE/OF45 Protein, CF

catalog :

3140-ME-050

quantity :

50 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Saito H, Chiba Ohkuma R, Yamakoshi Y, Karakida T, Yamamoto R, Shirai M, et al. Characterization of bioactive substances involved in the induction of bone augmentation using demineralized bone sheets. Int J Implant Dent. 2022;8:49 pubmed publisher
van der Meijden K, van Essen H, Bloemers F, Schulten E, Lips P, Bravenboer N. Regulation of CYP27B1 mRNA Expression in Primary Human Osteoblasts. Calcif Tissue Int. 2016;99:164-73 pubmed publisher
Kulkarni R, Bakker A, Everts V, Klein Nulend J. Inhibition of osteoclastogenesis by mechanically loaded osteocytes: involvement of MEPE. Calcif Tissue Int. 2010;87:461-8 pubmed publisher

product information

master code :

3140-ME

SKU :

3140-ME-050

product name :

Recombinant Human MEPE/OF45 Protein, CF

unit size :

50 ug

description :

The Recombinant Human MEPE/OF45 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human MEPE/OF45 Protein, CF has been validated for the following applications: Bioactivity.

target :

MEPE/OF45

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

82 kDa, reducing conditions

theoretical molecular weight :

57 kDa

gene symbol :

MEPE

details of functionality :

Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. rhMEPE, immobilized at 2 ╡g/mL (100 ╡L/well), can induce more than 60% of ATDC5 cell adhesion.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9NQ76

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human MEPE/OF45 protein Pro18-Asp525 & Phe20-Asp525 & Gln21-Asp525, all with a C-terminal 10-His tag

source short :

NS0

USD :

541 USD

alt names :

extracellular phosphoglycoprotein with ASARM motif (bone), matrix extracellular phosphoglycoprotein, OF45, Osteoregulin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage