Recombinant Human Granulysin Protein, CF | R&D Systems 3138-GN-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Granulysin Protein, CF

catalog :

3138-GN-025/CF

quantity :

25 ug

price :

442 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Wei H, Lin L, Wang C, Lee Y, Chen Y, Liao Y. Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin. PLoS ONE. 2016;11:e0156321 pubmed publisher
Longhi L, da Silva R, Fornazim M, Spago M, De Oliveira R, Nowill A, et al. Phenotypic and functional characterization of NK cells in human immune response against the dimorphic fungus Paracoccidioides brasiliensis. J Immunol. 2012;189:935-45 pubmed publisher
Tewary P, Yang D, de la Rosa G, Li Y, Finn M, Krensky A, et al. Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin. Blood. 2010;116:3465-74 pubmed publisher

product information

brand :

R&D Systems

master code :

3138-GN/CF

SKU :

3138-GN-025/CF

product name :

Recombinant Human Granulysin Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse FGF basic/FGF2/bFGF Protein from R&D Systems is derived from E. coli. The Recombinant Mouse FGF basic/FGF2/bFGF Protein has been validated for the following applications: Bioactivity.

target :

Granulysin

category :

Proteins and Enzymes

alt names :

D2S69Elymphocyte-activation gene 2, GNLY, granulysin, LAG2, LAG-2, Lymphokine, Lymphokine LAG-2, NKG5, NKG5519, Protein NKG5, TLA519, TLA519T-cell activation protein 519, T-lymphocyte activation gene 519

buffer :

Lyophilized from a 0.2 µm filtered solution in Sodium Citrate and NaCl.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

15 - 16 kDa, reducing conditions

theoretical molecular weight :

15.4 kDa

gene symbol :

GNLY

details of functionality :

Measured by its ability to induce RANTES secretion by THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 0.3-1 µg/mL, in the presence of 10 µg/mL of a cross-linking antibody Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P22749

applications :

Bioactivity

source :

NS0-derived Recombinant Human Granulysin Protein, CF

USD :

409

Jul-22 :

442 USD

sizes available :

25 ug

more info or order :

R&D Systems product webpage