Recombinant Rat IL-23 Protein | R&D Systems 3136-RL-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat IL-23 Protein

catalog :

3136-RL-010

quantity :

10 ug

price :

443 USD

citations: 3

Reference
Lauraine M, de Taffin de Tilques M, Melamed Kadosh D, Cherqaoui B, Rincheval V, Prevost E, et al. TGFβ signaling pathway is altered by HLA-B27 expression, resulting in pathogenic consequences relevant for spondyloarthritis. Arthritis Res Ther. 2024;26:131 pubmed publisher
Lee E, Kim N, Kang J, Yoon S, Lee H, Jung H, et al. Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive but not Dahl salt-resistant rats. Dis Model Mech. 2020;13: pubmed publisher
Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol. 2007;178:4466-72 pubmed

product information

master code :

3136-RL

SKU :

3136-RL-010

product name :

Recombinant Rat IL-23 Protein

unit size :

10 ug

description :

The Recombinant Rat IL-23 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Rat IL-23 Protein has been validated for the following applications: Bioactivity.

target :

IL-23

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Rat

observed molecular weight :

66 kDa, reducing conditions

theoretical molecular weight :

58.3 kDa

details of functionality :

Measured by its ability to induce IL-17 secretion by mouse splenocytes. Aggarwal, S. et al . (2003) J. Biol. Chem. 278 :1910. The ED50 for this effect is 0.1-0.5 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_072133 (p40) NP_569094 (p19)

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived rat IL-23 protein Rat IL-23 p40 (Met23 - Ser335) Accession # NP_072133 IGSGSSRGGSGSGGSGGGGSK Rat IL-23 p19 (Leu20 - Ala196) Accession # NP_569094 8-His tag N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

443 USD

alt names :

IL23, IL-23, IL-23 p19/IL-12 p40, IL-23A, IL-23-A, IL-23p19, IL-23p19/IL-12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, JKA3 induced upon T-cell activation, MGC79388, SGRF, SGRFIL-23 subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.