Recombinant Human FCRL3/FcRH3 His-tag Protein, CF | R&D Systems 3126-FCB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FCRL3/FcRH3 His-tag Protein, CF

catalog :

3126-FCB-050

quantity :

50 ug

price :

490 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Vondrakova J, Frolikova M, Ded L, Cerny J, Postlerova P, Palenikova V, et al. MAIA, Fc receptor-like 3, supersedes JUNO as IZUMO1 receptor during human fertilization. Sci Adv. 2022;8:eabn0047 pubmed publisher
Agarwal S, Kraus Z, Dement Brown J, Alabi O, Starost K, Tolnay M. Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA. Cell Rep. 2020;30:1292-1299.e3 pubmed publisher
Franco A, Damdinsuren B, Ise T, Dement Brown J, Li H, Nagata S, et al. Human Fc receptor-like 5 binds intact IgG via mechanisms distinct from those of Fc receptors. J Immunol. 2013;190:5739-46 pubmed publisher

product information

master code :

3126-FCB

SKU :

3126-FCB-050

product name :

Recombinant Human FCRL3/FcRH3 His-tag Protein, CF

unit size :

50 ug

description :

The Recombinant Human FCRL3/FcRH3 His-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FCRL3/FcRH3 His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

FCRL3/FcRH3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

observed molecular weight :

70-90 kDa, under reducing conditions.

theoretical molecular weight :

62 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human FCRL3/FcRH3 His-tag (Catalog # 3126-FCB) is immobilized at 2.00 ╡g/mL (100 ╡L/well), Normal Human IgG binds with an ED50 of 1.00-6.00 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q96P31.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human FCRL3/FcRH3 protein Arg14-Arg569, with a C-terminal 6-His tag

source short :

NS0

USD :

490 USD

alt names :

CD307c, Fc receptor homolog 3, Fc receptor-like 3, Fc receptor-like protein 3, FCRH3, fcR-like protein 3, hIFGP3, IFGP3, immunoglobulin superfamily receptor translocation associated protein 3, IRTA3, SPAP2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage