Recombinant Human Erythropoietin R Protein | R&D Systems 307-ER-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Erythropoietin R Protein

catalog :

307-ER-050

quantity :

50 ug

price :

458 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Mochida Y, Hara A, Oka M, Maesato K, Ishioka K, Moriya H, et al. Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multicenter Cross-Sectional Study. Biomedicines. 2022;10: pubmed publisher
Oshima M, Hara A, Toyama T, Jun M, Pollock C, Jardine M, et al. Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor. Kidney Int Rep. 2021;6:284-295 pubmed publisher
Chen Y, Feng H, Jeng S. Zinc Supplementation Stimulates Red Blood Cell Formation in Rats. Int J Mol Sci. 2018;19: pubmed publisher
Hara A, Furuichi K, Koshino A, Yasuda H, Tran T, Iwata Y, et al. Clinical and Pathological Significance of Autoantibodies to Erythropoietin Receptor in Type 2 Diabetic Patients With CKD. Kidney Int Rep. 2018;3:133-141 pubmed publisher
Miao S, Wang S, Cheng X, Li Y, Zhang Q, Li G, et al. Erythropoietin promoted the proliferation of hepatocellular carcinoma through hypoxia induced translocation of its specific receptor. Cancer Cell Int. 2017;17:119 pubmed publisher
Khankin E, Mutter W, Tamez H, Yuan H, Karumanchi S, Thadhani R. Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease. PLoS ONE. 2010;5:e9246 pubmed publisher
Junk A, Mammis A, Savitz S, Singh M, Roth S, Malhotra S, et al. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2002;99:10659-64 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

307-ER

SKU :

307-ER-050

product name :

Recombinant Human Erythropoietin R Protein

Description :

The Recombinant Human Erythropoietin R Protein from R&D Systems is derived from NS0. The Recombinant Human Erythropoietin R Protein has been validated for the following applications: Bioactivity.

target :

Erythropoietin R

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose and with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

32 kDa, reducing conditions

theoretical molecular weight :

25 kDa

gene symbol :

EPOR

details of functionality :

Measured by its ability to inhibit Epo-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 60-300 ng/mL in the presence of 0.2 U/mL of rhEpo.

endotoxin note :

<0.1 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P19235

applications :

Bioactivity

source :

NS0-derived Recombinant Human Erythropoietin R Protein

USD :

458 USD

alt names :

EpoR, EPO-R, erythropoietin receptor, MGC138358

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage