Recombinant Human Matrilin-2 Protein, CF | R&D Systems 3044-MN-050/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Matrilin-2 Protein, CF

catalog :

3044-MN-050/CF

quantity :

50 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
The E, de Graaf D, Zhai Y, Yao Q, Ao L, Fullerton D, et al. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proc Natl Acad Sci U S A. 2022;119:e2202577119 pubmed publisher
The E, Yao Q, Zhang P, Zhai Y, Ao L, Fullerton D, et al. Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells. Cells. 2020;9: pubmed publisher
Li F, Song R, Ao L, Reece T, Cleveland J, Dong N, et al. ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2017;37:1339-1351 pubmed publisher

product information

master code :

3044-MN/CF

SKU :

3044-MN-050/CF

product name :

Recombinant Human Matrilin-2 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Matrilin-2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Matrilin-2 Protein, CF has been validated for the following applications: Binding Activity.

target :

Matrilin-2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

120 kDa, reducing conditions

theoretical molecular weight :

103 kDa

gene symbol :

MATN2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rat tail Collagen I at 10 ╡g/mL (100 ╡L/well) can bind rhMatrilin-2 with a linear range of 16-1,000 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAH10444

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Matrilin-2 protein Arg24-Arg937, with a C-terminal 6-His tag

source short :

NS0

USD :

541 USD

alt names :

MATN2, matrilin 2, matrilin-2, Matrilin2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage