Recombinant Human EphA5 Protein, CF | R&D Systems 3036-A5-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA5 Protein, CF

catalog :

3036-A5-100

quantity :

100 ug

price :

499 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher
D Angelo S, Staquicini F, Ferrara F, Staquicini D, Sharma G, Tarleton C, et al. Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications. JCI Insight. 2018;3: pubmed publisher
Staquicini F, Qian M, Salameh A, Dobroff A, Edwards J, Cimino D, et al. Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer. J Biol Chem. 2015;290:7345-59 pubmed publisher
Hahn A, Kaufmann J, Wies E, Naschberger E, Panteleev Ivlev J, Schmidt K, et al. The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med. 2012;18:961-6 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3036-A5

SKU :

3036-A5-100

product name :

Recombinant Human EphA5 Protein, CF

Description :

The Recombinant Human EphA5 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human EphA5 Protein, CF has been validated for the following applications: Binding Activity.

target :

EphA5

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

75-85 kDa, reducing conditions

theoretical molecular weight :

58.4 kDa

gene symbol :

EPHA5

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human EphA5 at 2 µg/mL (100 µL/well) can bind recombinant mouse Ephrin-A2 Fc Chimera with a linear range of 0.16-10 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAI43428

applications :

Binding Activity

source :

NS0-derived Recombinant Human EphA5 Protein

USD :

499 USD

alt names :

Bsk, Cek7, EC 2.7.10, EC 2.7.10.1, Ehk1, EHK-1, EHK1Hek7, EK7, EPH homology kinase 1, Eph homology kinase-1, EPH receptor A5, EphA5, EPH-like kinase 7, ephrin type-A receptor 5, hEK7, receptor protein-tyrosine kinase HEK7, Rek7, TYRO4HEK7CEK7, tyrosine-protein kinase receptor EHK-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage