Recombinant Human EphA2 Protein, CF | R&D Systems 3035-A2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA2 Protein, CF

catalog :

3035-A2

quantity :

100 ug

price :

339 USD

citations: 6

Reference
Mukai M, Suruga N, Saeki N, Ogawa K. EphA receptors and ephrin-A ligands are upregulated by monocytic differentiation/maturation and promote cell adhesion and protrusion formation in HL60 monocytes. BMC Cell Biol. 2017;18:28 pubmed publisher
Takasugi M, Okada R, Takahashi A, Virya Chen D, Watanabe S, Hara E. Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2. Nat Commun. 2017;8:15729 pubmed publisher
Park S, Park S, Kim D, Pyo A, Kimura R, Sathirachinda A, et al. Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2. PLoS ONE. 2015;10:e0132976 pubmed publisher
Liao Chan S, Daine Matsuoka B, Heald N, Wong T, Lin T, Cai A, et al. Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. PLoS ONE. 2015;10:e0124708 pubmed publisher
Hahn A, Kaufmann J, Wies E, Naschberger E, Panteleev Ivlev J, Schmidt K, et al. The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med. 2012;18:961-6 pubmed publisher
Jackson D, Gooya J, Mao S, Kinneer K, Xu L, Camara M, et al. A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo. Cancer Res. 2008;68:9367-74 pubmed publisher

product information

brand :

R&D Systems

master code :

3035-A2

SKU :

3035-A2-100

product name :

Recombinant Human EphA2 Protein, CF

description :

The Recombinant Human EphA2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human EphA2 Protein, CF has been validated for the following applications: Binding Activity.

target :

EphA2

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

70-75 kDa, reducing conditions

theoretical molecular weight :

56.9 kDa

gene symbol :

EPHA2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rhEphA2 at 2 µg/mL (100 µL/well) can bind rmEphrin-A1/Fc Chimera with a linear range of 0.078-5 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

3035-A2

accessionNumbers :

P29317

applications :

Binding Activity

source :

Mouse myeloma cell line, NS0-derived human EphA2 protein Gln25-Asn534, with a C-terminal 6-His tag

2020 USD :

339

2021 USD :

339 USD

alt names :

ARCC2, EC 2.7.10, EC 2.7.10.1, Eck, ECKepithelial cell receptor protein tyrosine kinase, EPH receptor A2, EphA2, ephrin type-A receptor 2, Epithelial cell kinase, Myk2, Sek2, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.