product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TGF-beta RI/ALK-5 Fc Chimera Protein, CF
catalog :
3025-BR-050
quantity :
50 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed publisher
Walker R, Czepnik M, Goebel E, McCoy J, Vujic A, Cho M, et al. Structural basis for potency differences between GDF8 and GDF11. BMC Biol. 2017;15:19 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3025-BR
SKU :
3025-BR-050
product name :
Recombinant Human TGF-beta RI/ALK-5 Fc Chimera Protein, CF
Description :
The Recombinant Human TGF-beta RI/ALK-5 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TGF-beta RI/ALK-5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TGF-beta RI/ALK-5
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
40-60 kDa, reducing conditions
theoretical molecular weight :
37 kDa (monomer)
gene symbol :
TGFBR1
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human TGF-beta RII Fc Chimera (Catalog # 341-BR ) is immobilized at 1 µg/mL (100 µL/well), it binds Recombinant Human (rh) TGF-beta RI/ALK-5 Fc Chimera in the presence of rhTGF-beta 1. The concentration of rhTGF-beta RI Fc Chimera that produces 50% of the optimal binding response is approximately 0.05-0.4 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P36897
applications :
Bioactivity
source :
NS0-derived Recombinant Human TGF-beta RI/ALK-5 Fc Chimera Protein
USD :
423 USD
alt names :
AAT5, activin A receptor type II-like kinase, 53kD, activin A receptor type II-like kinase, 53kDa, Activin receptor-like kinase 5, ACVRLK4, ALK-5, ALK-5ALK5, EC 2.7.11, EC 2.7.11.30, LDS1A, LDS2A, Serine/threonine-protein kinase receptor R4, SKR4, TbetaR-I, TGFB1R1, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFbetaRI, TGFBR1, TGF-bRI, TGFR-1, transforming growth factor beta receptor I, transforming growth factor, beta receptor 1, transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD), Transforming growth factor-beta receptor type I
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.