| Reference |
|---|
Ma H, Li Q, Wong W, N Diaye E, Caplazi P, Bender H, et al. LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung. Sci Adv. 2023;9:eadf0133 pubmed publisher |
Han H, Yang Y, Han Z, Wang L, Dong L, Qi H, et al. NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells. 2023;12: pubmed publisher |
Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, et al. Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proc Natl Acad Sci U S A. 2023;120:e2213317120 pubmed publisher |
Kramer B, Corallo C, van den Heuvel A, Crawford J, Olivier T, Elstak E, et al. High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis. Sci Rep. 2022;12:16930 pubmed publisher |
Santerre K, Cortez Ghio S, Proulx S. TGF-β-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2022;63:3 pubmed publisher |
KNOX J, Bou Gharios G, Hamill K, Willoughby C. MiR-18a-5p Targets Connective Tissue Growth Factor Expression and Inhibits Transforming Growth Factor β2-Induced Trabecular Meshwork Cell Contractility. Genes (Basel). 2022;13: pubmed publisher |
Callaghan B, Lester K, Lane B, Fan X, Goljanek Whysall K, Simpson D, et al. Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-β2. Sci Rep. 2022;12:9564 pubmed publisher |
Utsunomiya A, Chino T, Kasamatsu H, Hasegawa T, Utsunomiya N, Luong V, et al. The compound LG283 inhibits bleomycin-induced skin fibrosis via antagonizing TGF-β signaling. Arthritis Res Ther. 2022;24:94 pubmed publisher |
Sobierajska K, Wawro M, Niewiarowska J. Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition. Int J Mol Sci. 2022;23: pubmed publisher |
Kasetti R, Maddineni P, Kodati B, Nagarajan B, Yacoub S. Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFβ2 Induced Primary Open Angle Glaucoma. Int J Mol Sci. 2021;22: pubmed publisher |
Liu Z, Taiyab A, West Mays J. MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens. Int J Mol Sci. 2021;22: pubmed publisher |
Takahashi E, Saruwatari J, Fujimoto T, Tanoue Y, Fukuda T, Inoue T. The effects of exosomes derived from trabecular meshwork cells on Schlemm's canal endothelial cells. Sci Rep. 2021;11:21942 pubmed publisher |
Hsiao C, Chang Y, Hsiao Y, Chen P, Hsieh M, Wu W, et al. Triamcinolone acetonide modulates TGF‑β2‑induced angiogenic and tissue‑remodeling effects in cultured human retinal pigment epithelial cells. Mol Med Rep. 2021;24: pubmed publisher |
Tabib T, Huang M, Morse N, Papazoglou A, Behera R, Jia M, et al. Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin. Nat Commun. 2021;12:4384 pubmed publisher |
Lopez N, Rangan R, Clark A, Tovar Vidales T. Mirna Expression in Glaucomatous and TGFβ2 Treated Lamina Cribrosa Cells. Int J Mol Sci. 2021;22: pubmed publisher |
Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed publisher |
Ota C, Ida Y, Ohguro H, Hikage F. ROCK inhibitors beneficially alter the spatial configuration of TGFβ2-treated 3D organoids from a human trabecular meshwork (HTM). Sci Rep. 2020;10:20292 pubmed publisher |
Matsumura T, Fujimoto T, Futakuchi A, Takihara Y, Watanabe Kitamura F, Takahashi E, et al. TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness. PLoS ONE. 2020;15:e0242626 pubmed publisher |
Yemanyi F, Vranka J, Raghunathan V. Glucocorticoid-induced cell-derived matrix modulates transforming growth factor β2 signaling in human trabecular meshwork cells. Sci Rep. 2020;10:15641 pubmed publisher |
Rathi S, Danford I, Gudiseva H, Verkuil L, Pistilli M, Vishwakarma S, et al. Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis. Cells. 2020;9: pubmed publisher |
Faralli J, Filla M, McDowell C, Peters D. Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice. PLoS ONE. 2020;15:e0237932 pubmed publisher |
Fan Y, Wei J, Guo L, Zhao S, Xu C, Sun H, et al. Osthole Reduces Mouse IOP Associated With Ameliorating Extracellular Matrix Expression of Trabecular Meshwork Cell. Invest Ophthalmol Vis Sci. 2020;61:38 pubmed publisher |
Meurer S, Tezcan O, Lammers T, Weiskirchen R. Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells. Cell Signal. 2020;74:109731 pubmed publisher |
Briggs D, Langford Smith A, Birchenough H, Jowitt T, Kielty C, Enghild J, et al. Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation. J Biol Chem. 2020;295:5278-5291 pubmed publisher |
Yonemura H, Futakuchi A, Inoue Mochita M, Fujimoto T, Takahashi E, Tanihara H, et al. DNA methyltransferase inhibitor suppresses fibrogenetic changes in human conjunctival fibroblasts. Mol Vis. 2019;25:382-390 pubmed |
Wei X, Zhang L, Zhou Z, Kwon O, Zhang Y, Nguyen H, et al. Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. Cell Stem Cell. 2019;24:753-768.e6 pubmed publisher |
Rutgers M, Bach F, Vonk L, van Rijen M, Akrum V, van Boxtel A, et al. PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation. PLoS ONE. 2019;14:e0213483 pubmed publisher |
Feng H, Zhao X, Guo Q, Feng Y, Ma M, Guo W, et al. Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis. Int J Biol Sci. 2019;15:507-521 pubmed publisher |
Kobayashi M, Tokuda K, Kobayashi Y, Yamashiro C, Uchi S, Hatano M, et al. Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor. Invest Ophthalmol Vis Sci. 2019;60:528-537 pubmed publisher |
Ozek C, Krolewski R, Buchanan S, Rubin L. Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice. Sci Rep. 2018;8:17293 pubmed publisher |
Abraham C, Ludwig M, Andrysik Z, Pandey A, Joshi M, Galbraith M, et al. ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas. Cell Rep. 2018;24:3224-3236 pubmed publisher |
Inoue Mochita M, Inoue T, Kojima S, Futakuchi A, Fujimoto T, Sato Ohira S, et al. Interleukin-6-mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells. J Biol Chem. 2018;293:10975-10984 pubmed publisher |
Tsai C, Wu S, Kau H, Wei Y. Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts. Sci Rep. 2018;8:7276 pubmed publisher |
Wagner J, Chavakis E, Rogg E, Muhly Reinholz M, Glaser S, Günther S, et al. Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report. Arterioscler Thromb Vasc Biol. 2018;38:1170-1177 pubmed publisher |
Tsutsumi Kuroda U, Inoue T, Futakuchi A, Shobayashi K, Takahashi E, Kojima S, et al. Decreased MCP-1/CCR2 axis-mediated chemotactic effect of conjunctival fibroblasts after transdifferentiation into myofibroblasts. Exp Eye Res. 2018;170:76-80 pubmed publisher |
Nishida J, Miyazono K, Ehata S. Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms. Oncogene. 2018;37:2197-2212 pubmed publisher |
Wu J, Chen X, Liu X, Huang S, He C, Chen B, et al. Autophagy regulates TGF-?2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells. Mol Med Rep. 2018;17:3607-3614 pubmed publisher |
Glover J, Wells K, Matthäus F, Painter K, Ho W, Riddell J, et al. Hierarchical patterning modes orchestrate hair follicle morphogenesis. PLoS Biol. 2017;15:e2002117 pubmed publisher |
Selvamurugan N, He Z, Rifkin D, Dabovic B, Partridge N. Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation. Stem Cells Int. 2017;2017:2450327 pubmed publisher |
Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher |
Futakuchi A, Inoue T, Fujimoto T, Kuroda U, Inoue Mochita M, Takahashi E, et al. Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA). Invest Ophthalmol Vis Sci. 2017;58:2421-2429 pubmed publisher |
Tellios N, Belrose J, Tokarewicz A, Hutnik C, Liu H, Leask A, et al. TGF-? induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma. Sci Rep. 2017;7:812 pubmed publisher |
Wojciechowski M, Mahmutovic L, Shu D, Lovicu F. ERK1/2 signaling is required for the initiation but not progression of TGF?-induced lens epithelial to mesenchymal transition (EMT). Exp Eye Res. 2017;159:98-113 pubmed publisher |
Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed publisher |
Roe M, Swain S, Sebrell T, Sewell M, Collins M, Perrino B, et al. Differential regulation of CD103 (αE integrin) expression in human dendritic cells by retinoic acid and Toll-like receptor ligands. J Leukoc Biol. 2017;101:1169-1180 pubmed publisher |
Torrejon K, Papke E, Halman J, Bergkvist M, Danias J, Sharfstein S, et al. TGF?2-induced outflow alterations in a bioengineered trabecular meshwork are offset by a rho-associated kinase inhibitor. Sci Rep. 2016;6:38319 pubmed publisher |
Gum S, Kim Y, Jung J, Kim I, Lee J, Lee K, et al. Cyclosporine A inhibits TGF-?2-induced myofibroblasts of primary cultured human pterygium fibroblasts. Biochem Biophys Res Commun. 2017;482:1148-1153 pubmed publisher |
Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, et al. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest. 2017;127:383-401 pubmed publisher |
JENKINS L, Singh P, Varadaraj A, Lee N, Shah S, Flores H, et al. Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling. J Biol Chem. 2016;291:25716-25728 pubmed |
VanOudenhove J, Medina R, Ghule P, Lian J, Stein J, Zaidi S, et al. Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling. Stem Cell Reports. 2016;7:884-896 pubmed publisher |
Arai K, Eguchi T, Rahman M, Sakamoto R, Masuda N, Nakatsura T, et al. A Novel High-Throughput 3D Screening System for EMT Inhibitors: A Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516. PLoS ONE. 2016;11:e0162394 pubmed publisher |
Roussa E, Speer J, Chudotvorova I, Khakipoor S, Smirnov S, Rivera C, et al. The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-?2. J Cell Sci. 2016;129:3485-98 pubmed publisher |
Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med. 2015;21:530-6 pubmed publisher |
Reeves S, Kolstad T, Lien T, Herrington Shaner S, Debley J. Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children. Respir Res. 2015;16:21 pubmed publisher |
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, et al. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci. 2015;56:1051-62 pubmed publisher |
Villarreal G, Chatterjee A, Oh S, Oh D, Kang M, Rhee D. Canonical wnt signaling regulates extracellular matrix expression in the trabecular meshwork. Invest Ophthalmol Vis Sci. 2014;55:7433-40 pubmed publisher |
Jakobsen R, Østrup E, Zhang X, Mikkelsen T, Brinchmann J. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE. 2014;9:e96615 pubmed publisher |
Gerhart J, Greenbaum M, Scheinfeld V, Fitzgerald P, Crawford M, Bravo Nuevo A, et al. Myo/Nog cells: targets for preventing the accumulation of skeletal muscle-like cells in the human lens. PLoS ONE. 2014;9:e95262 pubmed publisher |
Neumann C, Garreis F, Paulsen F, Hammer C, Birke M, Scholz M. Osteopontin is induced by TGF-?2 and regulates metabolic cell activity in cultured human optic nerve head astrocytes. PLoS ONE. 2014;9:e92762 pubmed publisher |
Echeverria C, Montorfano I, Hermosilla T, Armisen R, Velasquez L, Cabello Verrugio C, et al. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity. PLoS ONE. 2014;9:e94146 pubmed publisher |
Kimura K, Orita T, Fujitsu Y, Liu Y, Wakuta M, Morishige N, et al. Inhibition by female sex hormones of collagen gel contraction mediated by retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:2621-30 pubmed publisher |
Villarreal G, Chatterjee A, Oh S, Oh D, Rhee D. Pharmacological regulation of SPARC by lovastatin in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2014;55:1657-65 pubmed publisher |
Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, et al. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury. Stem Cells Transl Med. 2014;3:334-45 pubmed publisher |
Volkmann I, Kumarswamy R, Pfaff N, Fiedler J, Dangwal S, Holzmann A, et al. MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses. Circ Res. 2013;113:997-1003 pubmed publisher |
Kolpa H, Peal D, Lynch S, Giokas A, Ghatak S, Misra S, et al. miR-21 represses Pdcd4 during cardiac valvulogenesis. Development. 2013;140:2172-80 pubmed publisher |
Zhou X, Spittau B, Krieglstein K. TGF? signalling plays an important role in IL4-induced alternative activation of microglia. J Neuroinflammation. 2012;9:210 pubmed publisher |
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher |
Cursiefen C, Maruyama K, Bock F, Saban D, Sadrai Z, Lawler J, et al. Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes. J Exp Med. 2011;208:1083-92 pubmed publisher |
Gregory P, Bracken C, Smith E, Bert A, Wright J, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22:1686-98 pubmed publisher |
Craig E, Austin A, Vaillancourt R, Barnett J, Camenisch T. TGF?2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion. Exp Cell Res. 2010;316:3397-405 pubmed publisher |
Iwata J, Hosokawa R, Sanchez Lara P, Urata M, Slavkin H, Chai Y. Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells. J Biol Chem. 2010;285:4975-82 pubmed publisher |
Kuchtey J, Kallberg M, Gelatt K, Rinkoski T, Komaromy A, Kuchtey R. Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci. 2008;49:3438-48 pubmed publisher |
Barkho B, Song H, Aimone J, Smrt R, Kuwabara T, Nakashima K, et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006;15:407-21 pubmed |
Neurohr C, Nishimura S, Sheppard D. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am J Respir Cell Mol Biol. 2006;35:252-9 pubmed |
Close J, Gumuscu B, Reh T. Retinal neurons regulate proliferation of postnatal progenitors and Müller glia in the rat retina via TGF beta signaling. Development. 2005;132:3015-26 pubmed |
Nagineni C, Kutty V, Detrick B, Hooks J. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J Cell Physiol. 2005;203:35-43 pubmed |
Saika S, Kono Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, et al. Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice. Lab Invest. 2004;84:1245-58 pubmed |
Murphy S, Doré J, Edens M, Coffey R, Barnard J, Mitchell H, et al. Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells. Mol Biol Cell. 2004;15:2853-62 pubmed |
Wen F, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, et al. Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am J Respir Cell Mol Biol. 2004;30:816-22 pubmed |
Liu X, Kohyama T, Wang H, Zhu Y, Wen F, Kim H, et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1049-56 pubmed |
Jiang Y, Zhang M, Koishi K, McLennan I. TGF-beta 2 attenuates the injury-induced death of mature motoneurons. J Neurosci Res. 2000;62:809-13 pubmed |
Mozes M, Hodics T, Kopp J. Isoform specificity of commercially-available anti-TGF-beta antibodies. J Immunol Methods. 1999;225:87-93 pubmed |
