Recombinant Human Matrilin-3 Protein, CF | R&D Systems 3017-MN-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Matrilin-3 Protein, CF

catalog :

3017-MN-050

quantity :

50 ug

price :

541 USD

citations: 4

Reference
Lu X, Liu Y, Zhang Z. Matrilin-3 alleviates extracellular matrix degradation of nucleus pulposus cells via induction of IL-1 receptor antagonist. Eur Rev Med Pharmacol Sci. 2020;24:5231-5241 pubmed publisher
Yang X, Trehan S, Guan Y, Sun C, Moore D, Jayasuriya C, et al. Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem. 2014;289:34768-79 pubmed publisher
Wang Q, Rozelle A, Lepus C, Scanzello C, Song J, Larsen D, et al. Identification of a central role for complement in osteoarthritis. Nat Med. 2011;17:1674-9 pubmed publisher
Hills R, Mazzarella R, Fok K, Liu M, Nemirovskiy O, Leone J, et al. Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate. J Biol Chem. 2007;282:11101-9 pubmed

product information

master code :

3017-MN

SKU :

3017-MN-050

product name :

Recombinant Human Matrilin-3 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Matrilin-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Matrilin-3 Protein, CF has been validated for the following applications: Binding Activity.

target :

Matrilin-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

57 kDa, reducing conditions

theoretical molecular weight :

50.6 kDa

gene symbol :

NDUFC2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rhCOMP at 2 ╡g/mL (100 ╡L/well) can bind rhMatrilin-3 with a linear range of 1.5-100 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O15232

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Matrilin-3 protein Asp29-Arg486, with a C-terminal 6-His tag

source short :

NS0

USD :

541 USD

alt names :

DIPOA, EDM5, HOA, matrilin 3, matrilin-3, Matrilin3, NDUFC2, OADIP, OS2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.