Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF | R&D Systems 3015-KR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF

catalog :

3015-KR-050

quantity :

50 ug

price :

507 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Wauquier N, Petitdemange C, Tarantino N, Maucourant C, Coomber M, Lungay V, et al. HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2+ NK cells in Lassa virus infection. EBioMedicine. 2019;40:605-613 pubmed publisher
Cassidy S, Mukherjee S, Myint T, Mbiribindi B, North H, Traherne J, et al. Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individuals. Eur J Immunol. 2015;45:492-500 pubmed publisher
Fadda L, Korner C, Kumar S, van Teijlingen N, Piechocka Trocha A, Carrington M, et al. HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function. PLoS Pathog. 2012;8:e1002805 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3015-KR

SKU :

3015-KR-050

product name :

Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF

Description :

The Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

KIR2DL2/CD158b1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

65-75 kDa, reducing conditions

theoretical molecular weight :

51.2 kDa (monomer)

gene symbol :

KIR2DL2

details of functionality :

Measured by its ability to bind HEK293T human embryonic kidney cells in a flow cytometry assay. When 1 µg of Recombinant Human KIR2DL2/CD158b1 Fc Chimera is added to 5 x 105 HEK293T cells, 20% of the cells will bind to the protein.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P43627

applications :

Bioactivity

source :

NS0-derived Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein

USD :

507 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage