This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-3R alpha/CD123 Protein
catalog :
301-R3
quantity :
25 ug
price :
449 USD
citations: 2
Reference
Bonifant C, Szöor A, Torres D, Joseph N, Velasquez M, Iwahori K, et al. CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia. Mol Ther. 2016;24:1615-26 pubmed publisher
Li G, Li X, Wu H, Yang X, Zhang Y, Chen L, et al. CD123 targeting oncolytic adenoviruses suppress acute myeloid leukemia cell proliferation in vitro and in vivo. Blood Cancer J. 2014;4:e194 pubmed publisher
product information
brand :
R&D Systems
master code :
301-R3
SKU :
301-R3-025
product name :
Recombinant Human IL-3R alpha/CD123 Protein
description :
The Recombinant Human IL-3R alpha/CD123 Protein from R&D Systems is derived from NS0. The Recombinant Human IL-3R alpha/CD123 Protein has been validated for the following applications: Binding Activity.
target :
IL-3R alpha/CD123
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
theoretical molecular weight :
33 kDa
gene symbol :
IL3RA
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human IL-3 R alpha/CD123 is present at 1 µg/mL, the concentration of Recombinant Human IL-3 (Catalog # 203-IL ) that produces 50% of the optimal binding response is found to be approximately 8-40 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
301-R3
accessionNumbers :
P26951
applications :
Binding Activity
source :
Mouse myeloma cell line, NS0-derived human IL-3 R alpha/CD123 protein Lys20-Arg305
2020 USD :
449
2021 USD :
449 USD
alt names :
CD123, CD123 antigen, hIL3Ra, hIL-3Ra, IL-3 R alpha, IL-3 receptor subunit alpha, IL3R, IL3R alpha, IL-3R subunit alpha, IL3RA, IL-3RA, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, interleukin 3 receptor, alpha (low affinity), interleukin-3 receptor subunit alpha, MGC34174
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.