Recombinant Human IL-3R alpha/CD123 Protein | R&D Systems 301-R3-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-3R alpha/CD123 Protein

catalog :

301-R3-025

quantity :

25 ug

price :

552 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Bonifant C, Szöor A, Torres D, Joseph N, Velasquez M, Iwahori K, et al. CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia. Mol Ther. 2016;24:1615-26 pubmed publisher
Li G, Li X, Wu H, Yang X, Zhang Y, Chen L, et al. CD123 targeting oncolytic adenoviruses suppress acute myeloid leukemia cell proliferation in vitro and in vivo. Blood Cancer J. 2014;4:e194 pubmed publisher

image

image 1 :

Recombinant Human IL-3R alpha/CD123 Protein Binding Activity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

301-R3

SKU :

301-R3-025

product name :

Recombinant Human IL-3R alpha/CD123 Protein

Description :

The Recombinant Human IL-3R alpha/CD123 Protein from R&D Systems is derived from NS0. The Recombinant Human IL-3R alpha/CD123 Protein has been validated for the following applications: Binding Activity.

target :

IL-3R alpha

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

theoretical molecular weight :

33 kDa

gene symbol :

IL3RA

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human IL-3 R alpha/CD123 is present at 1 µg/mL, the concentration of Recombinant Human IL-3 (Catalog # 203-IL ) that produces 50% of the optimal binding response is found to be approximately 8-40 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P26951

applications :

Binding Activity

source :

NS0-derived Recombinant Human IL-3R alpha/CD123 Protein

USD :

552 USD

alt names :

CD123, CD123 antigen, hIL3Ra, hIL-3Ra, IL-3 R alpha, IL-3 receptor subunit alpha, IL3R, IL3R alpha, IL-3R subunit alpha, IL3RA, IL-3RA, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, interleukin 3 receptor, alpha (low affinity), interleukin-3 receptor subunit alpha, MGC34174

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage