product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse BTLA Fc Chimera Protein, CF
catalog :
3007-BT-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Hanson A, Elpek K, Duong E, Shallberg L, Fan M, Johnson C, et al. ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models. PLoS ONE. 2020;15:e0239595 pubmed publisher
product information
master code :
3007-BT
SKU :
3007-BT-050
product name :
Recombinant Mouse BTLA Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse BTLA Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BTLA Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
BTLA
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
60-70 kDa, reducing conditions
theoretical molecular weight :
44 kDa (monomer)
gene symbol :
Btla
details of functionality :
Measured in a competitive binding assay. When Recombinant Mouse HVEM/TNFRSF14 Fc Chimera (Catalog # 2516-HV ) is immobilized at 0.1 ╡g/mL (100 ╡L/well), Recombinant Mouse BTLA Fc Chimera inhibits 50% binding of biotinylated Recombinant Mouse BTLA Fc Chimera (0.2 ╡g/mL) at the concentration range of 0.3-1 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse BTLA Fc Chimera Protein Binding Activity
accessionNumbers :
Q32MV9
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived mouse BTLA protein Mouse BTLA Glu30-Gly176 (Lys173Glu) Accession # Q32MV9 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
B and T lymphocyte associated, B and T lymphocyte attenuator, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA1, CD272, CD272 antigen, FLJ16065, MGC129743
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.