Recombinant Human VEGF (aa 207-318) Protein, CF | R&D Systems 298-VS-005/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human VEGF (aa 207-318) Protein, CF

catalog :

298-VS-005/CF

quantity :

5 ug (also 25 ug)

price :

407 USD

citations: 12

Reference
Li S, Wang C, Montel Hagen A, Chen H, Lopez S, Zhou O, et al. Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. Cell Rep. 2023;42:112241 pubmed publisher
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Seo N, Polozova A, Zhang M, Yates Z, Cao S, Li H, et al. Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab. MAbs. 2018;10:678-691 pubmed publisher
Zacchigna S, Pattarini L, Zentilin L, Moimas S, Carrer A, Sinigaglia M, et al. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J Clin Invest. 2008;118:2062-75 pubmed publisher
Matsuda A, Fukuda S, Matsumoto K, Saito H. Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Am J Respir Cell Mol Biol. 2008;38:168-75 pubmed
Pan Q, Chathery Y, Wu Y, Rathore N, Tong R, Peale F, et al. Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J Biol Chem. 2007;282:24049-56 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Neria F, Caramelo C, Peinado H, Gonzalez Pacheco F, Deudero J, De Solis A, et al. Mechanisms of endothelial cell protection by blockade of the JAK2 pathway. Am J Physiol Cell Physiol. 2007;292:C1123-31 pubmed
Lake A, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret G, et al. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. J Biol Chem. 2006;281:37844-52 pubmed
Narazaki M, Tosato G. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood. 2006;107:3892-901 pubmed
Sun J, Phung T, Shiojima I, Felske T, Upalakalin J, Feng D, et al. Microvascular patterning is controlled by fine-tuning the Akt signal. Proc Natl Acad Sci U S A. 2005;102:128-33 pubmed
Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, et al. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci. 2004;45:368-74 pubmed

product information

master code :

298-VS/CF

SKU :

298-VS-005/CF

product name :

Recombinant Human VEGF (aa 207-318) Protein, CF

unit size :

5 ug (also 25 ug)

description :

The Recombinant Human VEGF (aa 207-318) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human VEGF (aa 207-318) Protein, CF has been validated for the following applications: Bioactivity.

target :

VEGF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

14.1 kDa (monomer)

gene symbol :

VEGFA

details of functionality :

Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al . (1990) Proc. Natl. Acad. Sci. USA 87 :1323. The ED50 for this effect is 0.75-3.75 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human VEGF (aa 207-318) Protein Bioactivity

accessionNumbers :

NP_001020541

applications :

Bioactivity

source long :

E. coli -derived human VEGF protein Ala207-Arg318

source short :

E. coli

USD :

407 USD

alt names :

MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.