product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Serum Amyloid A1 Protein, CF
catalog :
2948-SA-025
quantity :
25 ug
price :
432 USD
more info or order :
citations: 4
Reference
Yan J, Bai Y, Chen F, Zou X, Xu J, Huang A, et al. An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte-tumor cell crosstalk, local immunosuppression and tumor progression. Cell Res. 2023;: pubmed publisher
Farré Alins V, Palomino Antolin A, Narros Fernández P, López Rodríguez A, Decouty Pérez C, Muñoz Montero A, et al. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients. Biomedicines. 2021;9: pubmed publisher
Burgess E, Hoyt L, Randall M, Mank M, Bivona J, Eisenhauer P, et al. Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A. J Immunol. 2018;201:2377-2384 pubmed publisher
Shridas P, de Beer M, Webb N. High-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation. J Biol Chem. 2018;293:13257-13269 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
2948-SA
SKU :
2948-SA-025
product name :
Recombinant Mouse Serum Amyloid A1 Protein, CF
description :
The Recombinant Mouse Serum Amyloid A1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse Serum Amyloid A1 Protein, CF has been validated for the following applications: Bioactivity.
target :
Serum Amyloid A1
unit size :
25 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in Tris-HCl, NaCl, PEG and Imidazole.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
11 kDa, reducing conditions
theoretical molecular weight :
11.8 kDa
gene symbol :
Saa1
details of functionality :
Measured by its ability to induce TNF-alpha secretion by J774A.1 mouse reticulum cell sarcoma macrophage cells. The ED50 for this effect is 1.5-7.5 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P05366
applications :
Bioactivity
product keywords :
2948-SA, rmSAA1, rmSAA1, carrier-free, carrier free, 2948SA, cytokinegrowthfact, SAA 1, SA-A1, SA A21, Serum amyloid A 1
source :
E. coli-derived Recombinant Mouse Serum Amyloid A1 Protein, CF
USD :
423
USD 2025 :
432 USD
alt names :
MGC111216, PIG4, SAA, SAA1, SAA2, serum amyloid A protein, serum amyloid A1, TP53I4, tumor protein p53 inducible protein 4
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.