product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human LSECtin/CLEC4G Protein, CF
catalog :
2947-CL-050
quantity :
50 ug
price :
432 USD
more info or order :
citations: 2
Reference
Lan X, Yang T, Wang Y, Qu B, Rong S, Song N. Characterization of 405B8H3(D-E), a newly engineered high affinity chimeric LAG-3 antibody with potent antitumor activity. FEBS Open Bio. 2023;13:1253-1265 pubmed publisher
Mooney B, Torres Velez F, Doering J, Ehrbar D, Mantis N. Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin-Ab complexes. J Leukoc Biol. 2019;106:1161-1176 pubmed publisher
product information
master code :
2947-CL
SKU :
2947-CL-050
product name :
Recombinant Human LSECtin/CLEC4G Protein, CF
unit size :
50 ug
description :
The Recombinant Human LSECtin/CLEC4G Protein, CF from R&D Systems is derived from NS0. The Recombinant Human LSECtin/CLEC4G Protein, CF has been validated for the following applications: Binding Activity.
target :
LSECtin/CLEC4G
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
37 kDa, reducing conditions
theoretical molecular weight :
27.8 kDa
gene symbol :
CLEC4G
details of functionality :
Measured by its ability to bind Jurkat human acute T cell leukemia cells in a flow cytometry assay. A 2-8 fold increase in fluorescence intensity can be observed when Jurkat cells are stained with 10 ╡g/tube rhLSECtin/his and mouse anti-polyHistidine-PE as compared to cells stained with Mouse Anti-polyHistidine PE-conjugated Monoclonal Antibody (Catalog # IC050P ). Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_940894
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived human LSECtin/CLEC4G protein Ser54-Cys293, with an N-terminal 9-His tag
source short :
NS0
USD :
432 USD
alt names :
CLEC4G, C-type lectin domain family 4 member G, C-type lectin domain family 4, member G, C-type lectin superfamily 4, member G, DTTR431, liver and lymph node sinusoidal endothelial cell C-type lectin, LP2698, LSECtin, Q6UXB4, UNQ431
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.