Recombinant Mouse IL-19 Protein, CF | R&D Systems 2915-IL-025/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-19 Protein, CF

catalog :

2915-IL-025/CF

quantity :

25 ug

price :

443 USD

citations: 8

Reference
Zou J, Tan W, Li B, Wang Z, Li Y, Zeng J, et al. Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2022;63:9 pubmed publisher
Tsubaki M, Takeda T, Matsuda T, Yamamoto Y, Higashinaka A, Yamamoto K, et al. Interleukin 19 suppresses RANKL-induced osteoclastogenesis via the inhibition of NF-κB and p38MAPK activation and c-Fos expression in RAW264.7 cells. Cytokine. 2021;144:155591 pubmed publisher
Manni M, Mandalapu S, McHugh K, Elloso M, Dudas P, Alcorn J. Molecular Mechanisms of Airway Hyperresponsiveness in a Murine Model of Steroid-Resistant Airway Inflammation. J Immunol. 2016;196:963-77 pubmed publisher
Horiuchi H, Parajuli B, Wang Y, Azuma Y, Mizuno T, Takeuchi H, et al. Interleukin-19 acts as a negative autocrine regulator of activated microglia. PLoS ONE. 2015;10:e0118640 pubmed publisher
Uto Konomi A, Miyauchi K, Ozaki N, Motomura Y, Suzuki Y, Yoshimura A, et al. Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines. PLoS ONE. 2012;7:e40343 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Hoffman C, Park S, Daley E, Emson C, Louten J, Sisco M, et al. Interleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway responses to microbial products. PLoS ONE. 2011;6:e27629 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher

product information

master code :

2915-IL/CF

SKU :

2915-IL-025/CF

product name :

Recombinant Mouse IL-19 Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse IL-19 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse IL-19 Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-19

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

17.7 kDa

gene symbol :

Il19

details of functionality :

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R▀. The ED50 for this effect is 20.0-200 pg/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8CJ70

applications :

Bioactivity

source long :

E. coli -derived mouse IL-19 protein Leu25-Ala176, with an N-terminal Met

source short :

E. coli

USD :

443 USD

alt names :

IL-10C, IL19, IL-19, interleukin 19, MDA1, melanoma differentiation associated protein-like protein, NG.1Melanoma differentiation-associated protein-like protein, ZMDA1interleukin-19

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.