product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Human Holo-Transferrin Protein, CF
catalog :
2914-HT-100MG
quantity :
100 mg (also 1 g)
price :
133 USD
more info or order :
citations: 52
Reference
Zhang H, Zhang Q, Chen X, Wang M, Li L, Yu C. Establishment of a transgene-free iPS cell line (SDCHi008-A) from a young patient bearing a KCNQ2 mutation and suffering from Epilepsy. Stem Cell Res. 2024;80:103507 pubmed publisher
Zhang H, Zhang T, Wang Y, Shi J, Meng Y, Zhang Q, et al. Establishment of a transgene-free iPS cell line (SDCHi007-A) from a young patient bearing a ATP1A2 mutation and suffering from Epilepsy. Stem Cell Res. 2024;79:103490 pubmed publisher
Co H, Wu C, Lee Y, Chen S. Emergence of large-scale cell death through ferroptotic trigger waves. Nature. 2024;631:654-662 pubmed publisher
Bratti M, Stubbs E, Kolodych S, Souchet H, Kelly L, Merlin J, et al. INA03: A Potent Transferrin-Competitive Antibody-Drug Conjugate against CD71 for Safer Acute Leukemia Treatment. Mol Cancer Ther. 2024;23:1159-1175 pubmed publisher
Li Z, Liu C, Xin H, Lv Y, Gao M, Ma J, et al. Establishment of a non-integrated iPSC line (SDQLCHi043-A) from a male infant with propionic acidemia carrying compound heterozygote mutations in PCCB gene. Stem Cell Res. 2024;76:103352 pubmed publisher
Yang X, Fan Y, Li Y, Zhang H, Wang B, Guan J, et al. Generation and characterization of PBMCs-derived human induced pluripotent stem cell (iPSC) line SDQLCHi050-A from a healthy donor. Stem Cell Res. 2024;74:103266 pubmed publisher
Yang X, Zhang H, Gao M, Lv Y, Song W, Duan C, et al. An induced pluripotent stem cell line (SDQLCHi062-A) from a patient carrying a mutation in the PAX2 gene. Stem Cell Res. 2023;73:103260 pubmed publisher
Gao C, Liu Y, Liu N, Li Z, Yang X, Yang Y, et al. Establishment of human induced pluripotent stem cell line (SDQLCHi060-A) from a patient with AUTS2 syndrome carrying a heterozygous mutation in AUTS2 gene. Stem Cell Res. 2023;73:103242 pubmed publisher
Wang Y, Yang X, Zhang H, Liu N, Liu Y, Gai Z, et al. Generation of a transgene-free iPS cell line (SDQLCHi053-A) from a young girl carrying a heterozygous mutation (c.427C > T) in SYNGAP1 gene. Stem Cell Res. 2023;71:103132 pubmed publisher
Fan Y, Li Y, Yang X, Zhang H, Wang B, Guan J, et al. Generation and characterization of PBMCs-derived human induced pluripotent stem cell (iPSC) line SDQLCHi051-A from an autism spectrum disorder patient with compound CHD8 gene mutations. Stem Cell Res. 2023;69:103114 pubmed publisher
Martins G, Nonaka C, Rossi E, de Lima A, Adanho C, Oliveira M, et al. Evaluation of 2D and 3D Erythroid Differentiation Protocols Using Sickle Cell Disease and Healthy Donor Induced Pluripotent Stem Cells. Cells. 2023;12: pubmed publisher
Ai D, Yang X, Li X, Liu N, Xie X, Liu Y, et al. Generation of an induced pluripotent stem cell line SDPHi002-A from a patient with lung cancer. Stem Cell Res. 2023;69:103096 pubmed publisher
Badat M, Ejaz A, Hua P, Rice S, Zhang W, Hentges L, et al. Direct correction of haemoglobin E β-thalassaemia using base editors. Nat Commun. 2023;14:2238 pubmed publisher
Xi Y, Zhang H, Wang B, Song W, Liu Y. Establishment of an induced pluripotent stem cell line SDQLCHi049-A from a healthy male neonate. Stem Cell Res. 2023;69:103097 pubmed publisher
Chowdhury O, Ghosh S, Das A, Liu H, Shang P, Stepicheva N, et al. Sustained systemic inflammation increases autophagy and induces EMT/fibrotic changes in mouse liver cells: Protection by melatonin. Cell Signal. 2023;101:110521 pubmed publisher
Wang Y, Lv Y, Yang X, Li Y, Li Z, Gao Z, et al. Generation of an induced pluripotent stem cell line (SDQLCHi044-A) from a patient with autosomal dominant mental retardation type 5 harboring heterozygous mutation in SYNGAP1 gene. Stem Cell Res. 2022;64:102922 pubmed publisher
Truch J, Downes D, Scott C, G xfc r E, Telenius J, Repapi E, et al. The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin. Nat Commun. 2022;13:3485 pubmed publisher
Stevens Hernandez C, Flatt J, Kupzig S, Bruce L. Reticulocyte Maturation and Variant Red Blood Cells. Front Physiol. 2022;13:834463 pubmed publisher
Tipgomut C, Khuhapinant A, Wilson M, Poldee S, Heesom K, Metheetrairut C, et al. MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera. Sci Rep. 2021;11:22483 pubmed publisher
Li Z, Zhang X, Li X, Yang Y, Xin H, Yang X, et al. A non-integrated iPSC line (SDQLCHi042-A) from a boy suffering from familial combined hyperlipidemia with compound heterozygous mutations of lipoprotein lipase gene. Stem Cell Res. 2021;53:102313 pubmed publisher
Yamamoto R, Yoden E, Tanaka N, Kinoshita M, Imakiire A, Hirato T, et al. Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II. Mol Genet Metab Rep. 2021;27:100758 pubmed publisher
Zhang H, Liu C, Ma Y, Lin L, Lv Y, Gao M, et al. Generation of an induced pluripotent stem cell line SDQLCHi026-A from a hereditary tyrosinemia type I patient carrying compound heterozygote mutations in FAH gene. Stem Cell Res. 2021;53:102331 pubmed publisher
Barnier J, Euphrasie D, Join Lambert O, Audry M, Schönherr Hellec S, Schmitt T, et al. Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. PLoS Pathog. 2021;17:e1009299 pubmed publisher
Yang X, Liu N, Mu H, Lv Y, Zhang H, Li Y, et al. Reprogramming of human peripheral blood mononuclear cell (PBMC) from a patient suffering from hearing loss into iPSC line (SDQLCHi035-A) maintaining compound heterozygous variations in GJB2 gene. Stem Cell Res. 2021;51:102188 pubmed publisher
Yang X, Duan C, Zhang H, Li Y, Guan J, Wang D, et al. Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25. Stem Cell Res. 2021;51:102147 pubmed publisher
Wang B, Yang L, Li Y, Gao M, Zhang H, Yang X, et al. Establishment of a human induced pluripotent stem cell line (SDQLCHi037-A) from a patient with Alagille syndrome carrying heterozygous mutation in JAG1 gene. Stem Cell Res. 2021;51:102162 pubmed publisher
Zhang H, Zhang H, Ma Y, Lv Y, Gai Z, Liu Y. Generation and characterization of an induced pluripotent stem cell line SDQLCHi018-A from a congenital myasthenic syndrome patient carrying compound heterozygote mutations in RAPSN gene. Stem Cell Res. 2021;51:102160 pubmed publisher
Liu N, Yang X, Wang S, Dong R, Li Y, Lv Y, et al. PBMC-derived integration-free iPSCs line SDQLCHi039-A from a patient with X-linked agammaglobulinemia carrying a novel 9-bp in-frame deletion in BTK gene. Stem Cell Res. 2021;51:102165 pubmed publisher
Wang B, Liu C, Zhang H, Gai Z, Liu Y. An induced pluripotent stem cell line (SDQLCHi033-A) derived from a patient with maple syrup urine disease type Ib carrying a homozygous mutation in BCKDHB gene. Stem Cell Res. 2020;50:102146 pubmed publisher
Walczak J, Camargo Johnson M, MUTHUMALAIAPPAN K. Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology. Methods Protoc. 2020;3: pubmed publisher
Flatt J, Stevens Hernandez C, Cogan N, Eggleston D, Haines N, Heesom K, et al. Expression of South East Asian Ovalocytic Band 3 Disrupts Erythroblast Cytokinesis and Reticulocyte Maturation. Front Physiol. 2020;11:357 pubmed publisher
Tang X, Liu X, Chen Z, Luo L, Liu X, Deng J, et al. Using inducible lentiviral vectors to generate induced pluripotent stem cell line ZOCi001-A from peripheral blood cells of a patient with CRB1-/- retinitis pigmentosa. Stem Cell Res. 2020;45:101817 pubmed publisher
Di Matteo F, Pipicelli F, Kyrousi C, Tovecci I, Penna E, Crispino M, et al. Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy. EMBO Mol Med. 2020;12:e11419 pubmed publisher
Zhang H, Ma Y, Lv Y, Wan Y, Zhao Q, Gai Z, et al. An integration-free iPSC line SDQLCHi025-A from a girl with multiminicore disease carrying compound heterozygote mutations in RYR1 gene. Stem Cell Res. 2020;45:101775 pubmed publisher
Liu X, Yang X, Li Y, Wang X, Ma J, Jiang W, et al. Generation of patient-specific pluripotent induced stem cell line SDUBMSI002-A from a patient with X-linked mental retardation syndrome. Stem Cell Res. 2020;43:101724 pubmed publisher
Ma Y, Zhang H, Li X, Yang X, Li Y, Guan J, et al. An integration-free iPSC line (SDQLCHi017-A) derived from a patient with nemaline myopathy-2 disease carrying compound heterozygote mutations in NEB gene. Stem Cell Res. 2020;43:101729 pubmed publisher
Guan J, Li Z, Zhang H, Yang X, Ma Y, Li Y, et al. Generation of a Human iPSC line (SDQLCHi021-A) from a patient with methylmalonic acidemia cblC type carrying compound heterozygous mutations in MMAHC gene. Stem Cell Res. 2020;43:101709 pubmed publisher
Xiaojing W, Yanyan M, Ruonan D, Xiaolin L, Haiyan Z, Jian M, et al. Generation of a human induced pluripotent stem cell line (SDUBMSi001-A) from a hereditary spastic paraplegia patient carrying kif1a c.773C>T missense mutation. Stem Cell Res. 2020;43:101727 pubmed publisher
Yang X, Yan B, Zhang H, Ma Y, Zhou Q, Li Y, et al. Generation of an induced pluripotent stem cell line (SDQLCHi009-A) from a patient with 47,XXY and ornithine transcarbamylase deficiency carrying a hemizygote mutation in OTC. Stem Cell Res. 2020;43:101704 pubmed publisher
Pandey P, Tomney A, Woon M, Uth N, Shafighi F, Ngabo I, et al. End-to-End Platform for Human Pluripotent Stem Cell Manufacturing. Int J Mol Sci. 2019;21: pubmed publisher
Zhang H, Ma Y, Li X, Yang X, Li Y, Guan J, et al. An integration-free iPSC line (SDQLCHi013-A) derived from a patient with maple syrup urine disease carrying compound heterozygote mutations in BCKDHA gene. Stem Cell Res. 2019;41:101585 pubmed publisher
Zhang H, Ma Y, Yu S, Yang X, Li Y, Guan J, et al. Establishment of a human iPSC line (SDQLCHi010-A) from a patient with optic nerve malformation carrying a heterozygous mutation in PAX6 gene. Stem Cell Res. 2019;41:101611 pubmed publisher
Ma Y, Zhang H, Zhang S, Dong R, Yang X, Li Y, et al. An integration-free iPSC line (SDQLCHi012-A) derived from a patient with inflammatory bowel disease- 28 carrying compound heterozygote mutations in IL10RA gene. Stem Cell Res. 2019;41:101577 pubmed publisher
Li Y, Zhang H, Yan B, Ma Y, Yang X, Guan J, et al. An induced pluripotent stem cell line (SDQLCHi006-A) derived from a patient with maple syrup urine disease type Ib carrying compound heterozygous mutations of p.R168C and p.T322I in BCKDHB gene. Stem Cell Res. 2019;40:101579 pubmed publisher
Ma Y, Zhang H, Yang X, Li Y, Guan J, Lv Y, et al. Establishment of a human induced pluripotent stem cell line (SDQLCHi004-A) from a patient with nemaline myopathy-4 disease carrying heterozygous mutation in TPM2 gene. Stem Cell Res. 2019;40:101559 pubmed publisher
Martin R, Ikeda K, Cromer M, Uchida N, Nishimura T, Romano R, et al. Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. Cell Stem Cell. 2019;24:821-828.e5 pubmed publisher
Denis K, Le Bris M, Le Guennec L, Barnier J, Faure C, Gouge A, et al. Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease. Nat Microbiol. 2019;4:972-984 pubmed publisher
Poldee S, Metheetrairut C, Nugoolsuksiri S, Frayne J, Trakarnsanga K. Optimization of an erythroid culture system to reduce the cost of in vitro production of red blood cells. MethodsX. 2018;5:1626-1632 pubmed publisher
Hopkinson B, Desler C, Kalisz M, Vestentoft P, Juel Rasmussen L, Bisgaard H. Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage. Oxid Med Cell Longev. 2017;2017:5080128 pubmed publisher
Bergounioux J, Coureuil M, Belli E, Ly M, Cambillau M, Goudin N, et al. Experimental Evidence of Bacterial Colonization of Human Coronary Microvasculature and Myocardial Tissue during Meningococcemia. Infect Immun. 2016;84:3017-23 pubmed publisher
Huang X, Wang Y, Yan W, Smith C, Ye Z, Wang J, et al. Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation. Stem Cells. 2015;33:1470-9 pubmed publisher
Staquicini F, Ozawa M, Moya C, Driessen W, Barbu E, Nishimori H, et al. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest. 2011;121:161-73 pubmed publisher
product information
master code :
2914-HT
SKU :
2914-HT-100MG
product name :
Human Holo-Transferrin Protein, CF
unit size :
100 mg (also 1 g)
description :
The Human Holo-Transferrin Protein, CF from R&D Systems is derived from Human Plasma. The Human Holo-Transferrin Protein, CF has been validated for the following applications: Bioactivity.
target :
Holo-Transferrin
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in sterile water.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
76-81 kDa, reducing conditions
gene symbol :
TF
details of functionality :
Measured in a serum-free cell proliferation assay using MDCK canine kidney epithelial cells. Taub, M. et al . (1979) PNAS 76 :3338. The ED50 for this effect is 0.075-0.375 ╡g/mL. Optimal concentration depends on cell type as well as the application or research objectives.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
applications :
Bioactivity
source long :
Human plasma-derived Holo-Transferrin protein. The human plasma used for the isolation of this product were certified by the supplier to be HIV-1 and HBsAg negative at the time of shipment. Human blood products should always be treated in accordance with universal handling precautions.
source short :
Human Plasma
USD :
133 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.