Recombinant Human Alkaline Phosphatase/ALPL Protein, CF | R&D Systems 2909-AP-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Alkaline Phosphatase/ALPL Protein, CF

catalog :

2909-AP-010

quantity :

10 ug

price :

385 USD

citations: 4

Reference
Hong C, Menshikova E, Whiteside T, Jackson E. Assessment of ATP Metabolism to Adenosine by Ecto-Nucleotidases Carried by Tumor-Derived Small Extracellular Vesicles. Res Sq. 2024;: pubmed publisher
Pervan Steel C, Roy Chowdhury U, Sookdeo H, Casale R, Dosa P, Htoo T, et al. Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (KATP) Channel Opening Prodrug. Invest Ophthalmol Vis Sci. 2022;63:26 pubmed publisher
Sun Y, Rahbani J, Jedrychowski M, Riley C, Vidoni S, Bogoslavski D, et al. Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine. Nature. 2021;593:580-585 pubmed publisher
Pettengill M, Matute J, Tresenriter M, Hibbert J, Burgner D, Richmond P, et al. Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis. PLoS ONE. 2017;12:e0175936 pubmed publisher

product information

master code :

2909-AP

SKU :

2909-AP-010

product name :

Recombinant Human Alkaline Phosphatase/ALPL Protein, CF

unit size :

10 ug

description :

The Recombinant Human Alkaline Phosphatase/ALPL Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Alkaline Phosphatase/ALPL Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Alkaline Phosphatase/ALPL

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl, MgCl2 and ZnCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

65-75 kDa, reducing conditions

theoretical molecular weight :

54 kDa

gene symbol :

ALPL

details of functionality :

Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl phosphate (4-MUP). The specific activity is 30,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P05186

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Alkaline Phosphatase/ALPL protein Leu18-Ser502, with a C-terminal 6-His tag

source short :

NS0

USD :

385 USD

alt names :

Akp2, Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALP, TNSALPMGC167935

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.