Recombinant Mouse MMP-8 Protein, CF | R&D Systems 2904-MP-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse MMP-8 Protein, CF

catalog :

2904-MP-010

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Russo S, Cathomas F, Lin H, CHAN K, Li L, Cuttoli R, et al. Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Res Sq. 2023;: pubmed publisher
Wang X, Rojas Quintero J, Wilder J, Tesfaigzi Y, Zhang D, Owen C. Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces. J Immunol. 2019;202:3267-3281 pubmed publisher
Craig V, Quintero P, Fyfe S, Patel A, Knolle M, Kobzik L, et al. Profibrotic activities for matrix metalloproteinase-8 during bleomycin-mediated lung injury. J Immunol. 2013;190:4283-96 pubmed publisher
Suryawanshi A, Mulik S, Sharma S, Reddy P, Sehrawat S, Rouse B. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol. 2011;186:3653-65 pubmed publisher
Bénézech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, et al. Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010;184:4521-30 pubmed publisher
Gaggar A, Jackson P, Noerager B, O Reilly P, McQuaid D, Rowe S, et al. A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol. 2008;180:5662-9 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2904-MP

SKU :

2904-MP-010

product name :

Recombinant Mouse MMP-8 Protein, CF

Description :

The Recombinant Mouse MMP-8 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse MMP-8 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-8

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in MES, NaCl, CaCl2 and Brij-35.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

60-65 kDa doublet, reducing conditions

theoretical molecular weight :

52 kDa and 51 kDa

gene symbol :

Mmp8

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is 400 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_032637

applications :

Enzyme Activity

source :

CHO-derived Recombinant Mouse MMP-8 Protein

USD :

423 USD

alt names :

CLG1HNC, Collagenase 2, EC 3.4.24, EC 3.4.24.34, matrix metallopeptidase 8 (neutrophil collagenase), matrix metalloproteinase 8 (neutrophil collagenase), Matrix metalloproteinase-8, MMP8, MMP-8, neutrophil collagenase, PMNL collagenase, PMNL-CL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage