Recombinant Human Meprin beta Subunit/MEP1B Protein, CF | R&D Systems 2895-ZN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Meprin beta Subunit/MEP1B Protein, CF

catalog :

2895-ZN-010

quantity :

10 ug

price :

385 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Biasin V, Wygrecka M, Marsh L, Becker Pauly C, Brcic L, Ghanim B, et al. Meprin β contributes to collagen deposition in lung fibrosis. Sci Rep. 2017;7:39969 pubmed publisher
Tsuchiya S, Simmer J, Hu J, Richardson A, Yamakoshi F, Yamakoshi Y. Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp). J Bone Miner Res. 2011;26:220-8 pubmed publisher

product information

master code :

2895-ZN

SKU :

2895-ZN-010

product name :

Recombinant Human Meprin beta Subunit/MEP1B Protein, CF

unit size :

10 ug

description :

The Recombinant Human Meprin beta Subunit/MEP1B Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Meprin beta Subunit/MEP1B Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Meprin beta Subunit/MEP1B

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

85 kDa, reducing conditions

theoretical molecular weight :

66 kDa

gene symbol :

MEP1B

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2 (Catalog # ES004 ). The specific activity is 350 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_005916

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Meprin beta Subunit/MEP1B protein Leu21-Ser593 & Thr23-Ser593, both with a C-terminal 10-His tag

source short :

NS0

USD :

385 USD

alt names :

EC 3.4.24.63, endopeptidase-2, MEP1B, meprin A subunit beta, meprin A, beta, Meprin B, N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage