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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MIF Protein
catalog :
289-MF-002
quantity :
2 ug
price :
136 USD
more info or order :
citations: 30
Reference
Rigazio C, Mariz Ponte N, P xe9 rez Caballero E, Penas F, Goren N, Santamar xed a M, et al. The combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells. Microb Pathog. 2022;173:105881 pubmed publisher
Oh H, Kwak J, Kim B, Jin H, Park W, Choi S, et al. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth. Cells. 2020;9: pubmed publisher
Chen H, Xia W, Hou M. LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway. Stem Cell Res Ther. 2020;11:31 pubmed publisher
Hernández Palma L, García Arellano S, Bucala R, Llamas Covarrubias M, De la Cruz Mosso U, Oregon Romero E, et al. Functional MIF promoter haplotypes modulate Th17-related cytokine expression in peripheral blood mononuclear cells from control subjects and rheumatoid arthritis patients. Cytokine. 2019;115:89-96 pubmed publisher
Rijvers L, Melief M, van der Vuurst de Vries R, Stéphant M, van Langelaar J, Wierenga Wolf A, et al. The macrophage migration inhibitory factor pathway in human B cells is tightly controlled and dysregulated in multiple sclerosis. Eur J Immunol. 2018;48:1861-1871 pubmed publisher
Ietta F, Ferro E, Bevilacqua E, Benincasa L, Maioli E, Paulesu L. Role of the Macrophage Migration Inhibitory Factor (MIF) in the survival of first trimester human placenta under induced stress conditions. Sci Rep. 2018;8:12150 pubmed publisher
Lang J, Cheng Y, Rolfe A, Hammack C, Vera D, Kyle K, et al. An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection. Stem Cell Reports. 2018;11:348-362 pubmed publisher
Fraser J, Kemp S, Young L, Ross M, Prach M, Hutchison G, et al. Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations. Sci Rep. 2018;8:7506 pubmed publisher
Noh S, Lee W, Kim W, Lee Y, Yoon K. Expression of macrophage migration inhibitory factor in footpad skin lesions with diabetic neuropathy. Mol Pain. 2018;14:1744806918775482 pubmed publisher
Sugita S, Makabe K, Iwasaki Y, Fujii S, Takahashi M. Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells. Invest Ophthalmol Vis Sci. 2018;59:1719-1731 pubmed publisher
Sparkes A, De Baetselier P, Brys L, Cabrito I, Sterckx Y, Schoonooghe S, et al. Novel half-life extended anti-MIF nanobodies protect against endotoxic shock. FASEB J. 2018;32:3411-3422 pubmed publisher
Jalili R, Horecka J, Swartz J, Davis R, Persson H. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Proc Natl Acad Sci U S A. 2018;115:E925-E933 pubmed publisher
Kumar R, de Mooij T, Peterson T, Kaptzan T, Johnson A, Daniels D, et al. Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane. PLoS ONE. 2017;12:e0179012 pubmed publisher
Coban N, Güleç C, Özsait Selçuk B, Erginel Unaltuna N. CYP19A1, MIF and ABCA1 genes are targets of the ROR? in monocyte and endothelial cells. Cell Biol Int. 2017;41:163-176 pubmed publisher
No Y, Lee S, Kumar A, Yun C. HIF1α-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5. PLoS ONE. 2015;10:e0137513 pubmed publisher
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, et al. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci. 2015;56:1051-62 pubmed publisher
Patel P, Khan N, Rani M, Gupta D, Jameel S. The expression of HIV-1 Vpu in monocytes causes increased secretion of TGF-? that activates profibrogenic genes in hepatic stellate cells. PLoS ONE. 2014;9:e88934 pubmed publisher
Li J, Mo H, Xiong G, Zhang L, He J, Huang Z, et al. Tumor microenvironment macrophage inhibitory factor directs the accumulation of interleukin-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients. J Biol Chem. 2012;287:35484-95 pubmed publisher
Herrero L, Nelson M, Srikiatkhachorn A, Gu R, Anantapreecha S, Fingerle Rowson G, et al. Critical role for macrophage migration inhibitory factor (MIF) in Ross River virus-induced arthritis and myositis. Proc Natl Acad Sci U S A. 2011;108:12048-53 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Huang M, Patel K, Taub D, Longo D, Goetzl E. Human CD4- 8- T cells are a distinctive immunoregulatory subset. FASEB J. 2010;24:2558-66 pubmed publisher
Wadgaonkar R, Somnay K, Garcia J. Thrombin induced secretion of macrophage migration inhibitory factor (MIF) and its effect on nuclear signaling in endothelium. J Cell Biochem. 2008;105:1279-88 pubmed publisher
Gilliver S, Ruckshanthi J, Hardman M, Nakayama T, Ashcroft G. Sex dimorphism in wound healing: the roles of sex steroids and macrophage migration inhibitory factor. Endocrinology. 2008;149:5747-57 pubmed publisher
Amin M, Haas C, Zhu K, Mansfield P, Kim M, Lackowski N, et al. Migration inhibitory factor up-regulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 via Src, PI3 kinase, and NFkappaB. Blood. 2006;107:2252-61 pubmed
Matsumoto K, Maruyama N, Maruyama T, Ohnishi Y, Nonaka S, Inoshita A, et al. Elevated macrophage migration inhibitory factor (MIF) levels in the urine of patients with focal glomerular sclerosis. Clin Exp Immunol. 2005;139:338-47 pubmed
Paulesu L, Cateni C, Romagnoli R, Ietta F, Dantzer V. Variation in macrophage-migration-inhibitory-factor immunoreactivity during porcine gestation. Biol Reprod. 2005;72:949-53 pubmed
Chuang C, Hung C, Tsai M, Yeh T, Chuang Y. High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?. Crit Care Med. 2004;32:734-9 pubmed
Ashcroft G, Mills S, Lei K, Gibbons L, Jeong M, Taniguchi M, et al. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J Clin Invest. 2003;111:1309-18 pubmed
Matsumoto K, Kanmatsuse K. Urinary levels of macrophage migration inhibitory factor in patients with IgA nephropathy. Nephron. 2002;92:309-15 pubmed
Wang L, Das H, Kamath A, Li L, Bukowski J. Human V gamma 2V delta 2 T cells augment migration-inhibitory factor secretion and counteract the inhibitory effect of glucocorticoids on IL-1 beta and TNF-alpha production. J Immunol. 2002;168:4889-96 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
289-MF
SKU :
289-MF-002
product name :
Recombinant Human MIF Protein
Description :
The Recombinant Human MIF Protein from R&D Systems is derived from E. coli. The Recombinant Human MIF Protein has been validated for the following applications: Bioactivity.
target :
MIF
category :
Proteins and Enzymes
unit size :
2 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MES and NaCl with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
theoretical molecular weight :
12.4 kDa 12.3 kDa
gene symbol :
MIF
details of functionality :
Bioassay data are not available.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA36315
applications :
Bioactivity
source :
E. coli-derived Recombinant Human MIF Protein
USD :
136 USD
alt names :
EC 5.3.2.1, EC 5.3.3.12, GIFmacrophage migration inhibitory factor, GLIF, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, macrophage migration inhibitory factor (glycosylation-inhibiting factor), MMIF, Phenylpyruvate tautomerase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.