protein

Recombinant Human Thrombopoietin GMP Protein, CF

288E-GMP-050

50 ug (also 1 mg)

288E-GMP-050

Recombinant Human Thrombopoietin GMP Protein, CF

50 ug (also 1 mg)

The Recombinant Human Thrombopoietin GMP Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Thrombopoietin GMP Protein, CF has been validated for the following applications: Bioactivity.

Thrombopoietin/Tpo

Proteins and Enzymes

Lyophilized from a 0.2 ╡m filtered solution in Sodium Acetate.

Unconjugated

Human

19 kDa, reducing conditions

18.7 kDa

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is 1 x 107 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).

<0.10 EU per 1 ╡g of the protein by the LAL method.

Recombinant Human Thrombopoietin GMP Protein Bioactivity

NP_000451.1

Bioactivity

E. coli -derived human Thrombopoietin/Tpo protein Ser22-Leu195 Produced in an animal-free laboratory. Manufactured and tested under cGMP guidelines

E. coli

Animal Free

Animal Free

Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, megakaryocyte stimulating factor, MGDF, MGDFC-mpl ligand, MKCSF, MK-CSF, ML, MPL ligand, MPLLG, MPLLGMGC163194, Myeloproliferative leukemia virus oncogene ligand, THCYT1, THPO, thrombopoietin, thrombopoietin nirs variant 1, Tpo, TPOMKCSF

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at <= -20 ░C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.