Recombinant Human Thrombopoietin (NS0-expressed) Protein, CF | R&D Systems 288-TPN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Thrombopoietin (NS0-expressed) Protein, CF

catalog :

288-TPN

quantity :

10 ug

price :

199 USD

citations: 6

Reference
Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, et al. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS ONE. 2011;6:e22261 pubmed publisher
Uchida N, Hsieh M, Hayakawa J, Madison C, Washington K, Tisdale J. Optimal conditions for lentiviral transduction of engrafting human CD34+ cells. Gene Ther. 2011;18:1078-86 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp Hematol. 2008;36:1121-31 pubmed publisher
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
Manz M, Miyamoto T, Akashi K, Weissman I. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A. 2002;99:11872-7 pubmed

product information

brand :

R&D Systems

master code :

288-TPN

SKU :

288-TPN-010/CF

product name :

Recombinant Human Thrombopoietin (NS0-expressed) Protein, CF

description :

The Recombinant Human Thrombopoietin (NS0-expressed) Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Thrombopoietin (NS0-expressed) Protein, CF has been validated for the following applications: Bioactivity.

target :

Thrombopoietin/THPO

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

80-90 kDa, reducing conditions

theoretical molecular weight :

35 kDa

gene symbol :

THPO

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=proteinsandenzymes

details of functionality :

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 5-15 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

288-TPN/CF

accessionNumbers :

P40225

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human Thrombopoietin/Tpo protein Ser22-Gly353

extended description :

A new economical version of TPO made in E. coli is now available.

2020 USD :

199

2021 USD :

199 USD

product details :

A new economical version of TPO made in E. coli is now available.

alt names :

Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, megakaryocyte stimulating factor, MGDF, MGDFC-mpl ligand, MKCSF, MK-CSF, ML, MPL ligand, MPLLG, MPLLGMGC163194, Myeloproliferative leukemia virus oncogene ligand, THCYT1, THPO, thrombopoietin, thrombopoietin nirs variant 1, Tpo, TPOMKCSF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.