Reference |
---|
Li S, Wang C, Montel Hagen A, Chen H, Lopez S, Zhou O, et al. Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. Cell Rep. 2023;42:112241 pubmed publisher
|
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, et al. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia. EMBO Mol Med. 2022;:e15631 pubmed publisher
|
Michaels Y, Edgar J, Major M, Castle E, Zimmerman C, Yin T, et al. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells. Sci Adv. 2022;8:eabn5522 pubmed publisher
|
Skokowa J, Hernandez Alvarez B, Coles M, Ritter M, Nasri M, Haaf J, et al. A topological refactoring design strategy yields highly stable granulopoietic proteins. Nat Commun. 2022;13:2948 pubmed publisher
|
Hayashi Y, Kawabata K, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, et al. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis. Cell Rep. 2022;39:110805 pubmed publisher
|
Sahoo S, Pastor V, Goodings C, Voss R, Kozyra E, Szvetnik A, et al. Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med. 2021;27:1806-1817 pubmed publisher
|
Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, et al. A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 2021;36:109576 pubmed publisher
|
Kato H, Maezawa Y, Ouchi Y, Takayama N, Sone M, Sone K, et al. Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome. Stem Cell Res. 2021;53:102360 pubmed publisher
|
Newby G, Yen J, Woodard K, Mayuranathan T, Lazzarotto C, Li Y, et al. Base editing of haematopoietic stem cells rescues sickle cell disease in mice. Nature. 2021;595:295-302 pubmed publisher
|
Borst S, Nations C, Klein J, Pavani G, Maguire J, Camire R, et al. Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model. Stem Cell Reports. 2021;16:1458-1467 pubmed publisher
|
Wang T, Pine A, Kotini A, Yuan H, Zamparo L, Starczynowski D, et al. Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets. Cell Stem Cell. 2021;28:1074-1089.e7 pubmed publisher
|
Chagraoui J, Girard S, Spinella J, Simon L, Bonneil E, Mayotte N, et al. UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex. Cell Stem Cell. 2021;28:48-62.e6 pubmed publisher
|
Yang L, Han Y, Nilsson Payant B, Gupta V, Wang P, Duan X, et al. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020;27:125-136.e7 pubmed publisher
|
Wesely J, Kotini A, Izzo F, Luo H, Yuan H, Sun J, et al. Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells. Cell Rep. 2020;31:107688 pubmed publisher
|
Spivak J, Merchant A, Williams D, Rogers O, Zhao W, Duffield A, et al. Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera. PLoS ONE. 2020;15:e0232801 pubmed publisher
|
Norbnop P, Ingrungruanglert P, Israsena N, Suphapeetiporn K, Shotelersuk V. Generation and characterization of HLA-universal platelets derived from induced pluripotent stem cells. Sci Rep. 2020;10:8472 pubmed publisher
|
Zou Z, Fan X, Liu Y, Sun Y, Zhang X, Sun G, et al. Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling. J Cell Mol Med. 2020;24:6644-6657 pubmed publisher
|
Leonard A, Yapundich M, Nassehi T, Gamer J, Drysdale C, Haro Mora J, et al. Low-Dose Busulfan Reduces Human CD34+ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice. Mol Ther Methods Clin Dev. 2019;15:430-437 pubmed publisher
|
Fukushima T, Tanaka Y, Hamey F, Chang C, Oki T, Asada S, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29:4144-4158.e7 pubmed publisher
|
Chagraoui J, Lehnertz B, Girard S, Spinella J, Fares I, Tomellini E, et al. UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal. PLoS ONE. 2019;14:e0224900 pubmed publisher
|
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed publisher
|
Uchida N, Hsieh M, Raines L, Haro Mora J, Demirci S, Bonifacino A, et al. Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders. Nat Commun. 2019;10:4479 pubmed publisher
|
Roman Rodriguez F, Ugalde L, Alvarez L, Díez B, Ramirez M, Risueño C, et al. NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia. Cell Stem Cell. 2019;25:607-621.e7 pubmed publisher
|
Rogers G, Chen H, Morales H, Cannon P. Homologous Recombination-Based Genome Editing by Clade F AAVs Is Inefficient in the Absence of a Targeted DNA Break. Mol Ther. 2019;27:1726-1736 pubmed publisher
|
Tomellini E, Fares I, Lehnertz B, Chagraoui J, Mayotte N, Macrae T, et al. Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells. Cell Rep. 2019;28:1063-1073.e5 pubmed publisher
|
Kinney M, Vo L, Frame J, Barragan J, Conway A, Li S, et al. A systems biology pipeline identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019;37:810-818 pubmed publisher
|
Nasri M, Ritter M, Mir P, Dannenmann B, Aghaallaei N, Amend D, et al. CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients. Haematologica. 2019;: pubmed publisher
|
Capitano M, Mor Vaknin N, Saha A, Cooper S, Legendre M, Guo H, et al. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. J Clin Invest. 2019;129:2555-2570 pubmed publisher
|
Ruiz Gutierrez M, Bölükbaşı Ö, Alexe G, Kotini A, Ballotti K, Joyce C, et al. Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. JCI Insight. 2019;5: pubmed publisher
|
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed publisher
|
Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, et al. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I. Stem Cell Res. 2019;36:101406 pubmed publisher
|
Uchida N, Nassehi T, Drysdale C, Gamer J, Yapundich M, Demirci S, et al. High-Efficiency Lentiviral Transduction of Human CD34+ Cells in High-Density Culture with Poloxamer and Prostaglandin E2. Mol Ther Methods Clin Dev. 2019;13:187-196 pubmed publisher
|
Kaur M, Drake A, Hu G, Rudnick S, Chen Q, Phennicie R, et al. Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice. J Immunol. 2019;202:1885-1894 pubmed publisher
|
Huang X, Guo B, Liu S, Wan J, Broxmeyer H. Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment. Nat Commun. 2018;9:2741 pubmed publisher
|
Camgoz A, Paszkowski Rogacz M, Satpathy S, Wermke M, Hamann M, von Bonin M, et al. STK3 is a therapeutic target for a subset of acute myeloid leukemias. Oncotarget. 2018;9:25458-25473 pubmed publisher
|
Cesana M, Guo M, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 2018;22:575-588.e7 pubmed publisher
|
Tkaczynski E, Arulselvan A, Tkaczynski J, Avery S, Xiao L, Torok Storb B, et al. 2-O, 3-O desulfated heparin mitigates murine chemotherapy- and radiation-induced thrombocytopenia. Blood Adv. 2018;2:754-761 pubmed publisher
|
Zheng S, Papalexi E, Butler A, STEPHENSON W, Satija R. Molecular transitions in early progenitors during human cord blood hematopoiesis. Mol Syst Biol. 2018;14:e8041 pubmed publisher
|
Palau A, Garz A, Diesch J, Zwick A, Malinverni R, Valero V, et al. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Oncotarget. 2017;8:115002-115017 pubmed publisher
|
Palpant N, Wang Y, Hadland B, Zaunbrecher R, Redd M, Jones D, et al. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis. Cell Rep. 2017;20:1597-1608 pubmed publisher
|
Lee J, Salci K, Reid J, Orlando L, Tanasijevic B, Shapovalova Z, et al. Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations. Stem Cells. 2017;35:2095-2102 pubmed publisher
|
Huang J, Khan A, Au B, Barber D, Lopez Vasquez L, Prokopishyn N, et al. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017;5:241-258 pubmed publisher
|
Sugimura R, Jha D, Han A, Soria Valles C, da Rocha E, Lu Y, et al. Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017;545:432-438 pubmed publisher
|
Shaw K, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, et al. Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency. J Clin Invest. 2017;127:1689-1699 pubmed publisher
|
Guo B, Huang X, Cooper S, Broxmeyer H. Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment. Nat Med. 2017;23:424-428 pubmed publisher
|
Kotini A, Chang C, Chow A, Yuan H, Ho T, Wang T, et al. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia. Cell Stem Cell. 2017;20:315-328.e7 pubmed publisher
|
Baccelli I, Krosl J, Boucher G, Boivin I, Lavallée V, Hébert J, et al. A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens. Blood Cancer J. 2017;7:e529 pubmed publisher
|
Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota S, Ota Y, et al. Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes. Immunology. 2017;150:64-73 pubmed publisher
|
Mori Y, Chen J, Pluvinage J, Seita J, Weissman I. Prospective isolation of human erythroid lineage-committed progenitors. Proc Natl Acad Sci U S A. 2015;112:9638-43 pubmed publisher
|
Jiang X, Lim C, Li Z, Lee P, Yatim S, Guan P, et al. Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML). PLoS ONE. 2015;10:e0122983 pubmed publisher
|
Baldwin K, Urbinati F, Romero Z, Campo Fernandez B, Kaufman M, Cooper A, et al. Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells. 2015;33:1532-42 pubmed publisher
|
Shaham L, Vendramini E, Ge Y, Goren Y, Birger Y, Tijssen M, et al. MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome. Blood. 2015;125:1292-301 pubmed publisher
|
Barese C, Felizardo T, Sellers S, Keyvanfar K, Di Stasi A, Metzger M, et al. Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques. Stem Cells. 2015;33:91-100 pubmed publisher
|
Shen S, Xu N, Klamer G, Ko K, Khoo M, Ma D, et al. Small-molecule inhibitor of glycogen synthase kinase 3β 6-Bromoindirubin-3-oxime inhibits hematopoietic regeneration in stem cell recipient mice. Stem Cells Dev. 2015;24:724-36 pubmed publisher
|
Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, et al. Targeted 25-hydroxyvitamin D3 1α-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Mol Ther. 2015;23:339-51 pubmed publisher
|
Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, et al. Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies. Sci Rep. 2014;4:6136 pubmed publisher
|
Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, et al. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood. 2014;124:1393-403 pubmed publisher
|
Rosen D, Leung L, Louie B, Cordeiro J, Conroy A, Shapira I, et al. Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP). J Transl Med. 2014;12:184 pubmed publisher
|
Chaurasia P, Gajzer D, Schaniel C, D Souza S, Hoffman R. Epigenetic reprogramming induces the expansion of cord blood stem cells. J Clin Invest. 2014;124:2378-95 pubmed publisher
|
Wu C, Li B, Lu R, Koelle S, Yang Y, Jares A, et al. Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell. 2014;14:486-499 pubmed publisher
|
Nakamura S, Takayama N, Hirata S, Seo H, Endo H, Ochi K, et al. Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells. Cell Stem Cell. 2014;14:535-48 pubmed publisher
|
Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S. MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells. Stem Cells. 2014;32:1337-46 pubmed publisher
|
Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, et al. A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation. Blood. 2014;123:1239-49 pubmed publisher
|
Sjeklocha L, Wong P, Belcher J, Vercellotti G, Steer C. ?-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. PLoS ONE. 2013;8:e80403 pubmed publisher
|
Uchida N, Weitzel R, Evans M, Green R, Bonifacino A, Krouse A, et al. Evaluation of engraftment and immunological tolerance after reduced intensity conditioning in a rhesus hematopoietic stem cell gene therapy model. Gene Ther. 2014;21:148-57 pubmed publisher
|
Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein I, et al. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood. 2014;123:650-8 pubmed publisher
|
Shinohara A, Imai Y, Nakagawa M, Takahashi T, Ichikawa M, Kurokawa M. Intracellular reactive oxygen species mark and influence the megakaryocyte-erythrocyte progenitor fate of common myeloid progenitors. Stem Cells. 2014;32:548-57 pubmed publisher
|
Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, et al. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 2013;13:459-70 pubmed publisher
|
Dasouki M, Rafi S, Olm Shipman A, Wilson N, Abhyankar S, Ganter B, et al. Exome sequencing reveals a thrombopoietin ligand mutation in a Micronesian family with autosomal recessive aplastic anemia. Blood. 2013;122:3440-9 pubmed publisher
|
Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, et al. Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther. 2013;21:1044-54 pubmed publisher
|
Lee M, Prasain N, Chae H, Kim Y, Mantel C, Yoder M, et al. Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming. Stem Cells. 2013;31:666-81 pubmed publisher
|
Jawad M, Yu N, Seedhouse C, Tandon K, Russell N, Pallis M. Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer. 2012;12:431 pubmed publisher
|
Kodama T, Hikita H, Kawaguchi T, Shigekawa M, Shimizu S, Hayashi Y, et al. Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages. Cell Death Differ. 2012;19:1856-69 pubmed publisher
|
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
|
Bauer T, Olson E, Huo Y, Tuschong L, Allen J, Li Y, et al. Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter. Gene Ther. 2011;18:553-9 pubmed publisher
|
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
|
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
|
Gunetti M, Ferrero I, Rustichelli D, Berger M, Gammaitoni L, Timeus F, et al. Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions. Exp Hematol. 2008;36:235-43 pubmed publisher
|
Bogatkevich G, Ludwicka Bradley A, Highland K, Hant F, Nietert P, Singleton C, et al. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum. 2007;56:2432-42 pubmed
|
Srivastava A, Nedelcu E, Esmaeli Azad B, Mishra R, Carrier E. Thrombopoietin enhances generation of CD34+ cells from human embryonic stem cells. Stem Cells. 2007;25:1456-61 pubmed
|
Reinhold A, Zhang J, Gessner R, Felderhoff Mueser U, Obladen M, Dame C. High thrombopoietin concentrations in the cerebrospinal fluid of neonates with sepsis and intraventricular hemorrhage may contribute to brain damage. J Interferon Cytokine Res. 2007;27:137-45 pubmed
|
Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, et al. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells. Stem Cells. 2006;24:2014-22 pubmed
|
Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, et al. Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells. Exp Hematol. 2006;34:760-9 pubmed
|
Kahl C, Tarantal A, Lee C, Jimenez D, Choi C, Pepper K, et al. Effects of busulfan dose escalation on engraftment of infant rhesus monkey hematopoietic stem cells after gene marking by a lentiviral vector. Exp Hematol. 2006;34:369-81 pubmed
|
Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, et al. Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ. 2006;13:1686-96 pubmed
|
Corazza F, Hermans C, D Hondt S, Ferster A, Kentos A, Benoit Y, et al. Circulating thrombopoietin as an in vivo growth factor for blast cells in acute myeloid leukemia. Blood. 2006;107:2525-30 pubmed
|
Drouet M, Mathieu J, Grenier N, Multon E, Sotto J, Herodin F. The reduction of in vitro radiation-induced Fas-related apoptosis in CD34+ progenitor cells by SCF, FLT-3 ligand, TPO, and IL-3 in combination resulted in CD34+ cell proliferation and differentiation. Stem Cells. 1999;17:273-85 pubmed
|