Recombinant Human Siglec-6/CD327 Fc Chimera Protein, CF | R&D Systems 2859-SL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Siglec-6/CD327 Fc Chimera Protein, CF

catalog :

2859-SL

quantity :

50 ug

price :

359 USD

citations: 2

Reference
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Lam K, Chiu P, Lee C, Pang R, Leung C, Koistinen H, et al. Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway. J Biol Chem. 2011;286:37118-27 pubmed publisher

product information

brand :

R&D Systems

master code :

2859-SL

SKU :

2859-SL-050

product name :

Recombinant Human Siglec-6/CD327 Fc Chimera Protein, CF

description :

The Recombinant Human Siglec-6/CD327 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Siglec-6/CD327 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Siglec-6/CD327

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

80-95 kDa, reducing conditions

theoretical molecular weight :

60.3 kDa (monomer)

gene symbol :

SIGLEC6

details of functionality :

Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn). Patel, N. et al . (1999) The Journal of Biological Chemistry 274 :22729.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

2859-SL

accessionNumbers :

NP_942142

applications :

Binding Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human Siglec-6/CD327 protein Human Siglec-6 (Gln27-Val331) Accession # NP_942142 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

2020 USD :

359

2021 USD :

359 USD

alt names :

CD327, CD327 antigen, CD33 antigen-like 1, CD33L1, CD33L1OBBP1CD327, CD33L2, CD33LCDW327, CDw327, OB-BP1, Obesity-binding protein 1, sialic acid binding Ig-like lectin 6, sialic acid-binding Ig-like lectin 6, Siglec6, Siglec-6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.