product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Glypican 6 Protein, CF
catalog :
2845-GP-050
quantity :
50 ug
price :
541 USD
more info or order :
citations: 5
Reference
Li N, Quan A, Li D, Pan J, Ren H, Hoeltzel G, et al. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nat Commun. 2023;14:1986 pubmed publisher
Colin Pierre C, Untereiner V, Sockalingum G, Ramont L, Br xe9 zillon S. Investigation of Glypican-4 and -6 by Infrared Spectral Imaging during the Hair Growth Cycle. Int J Mol Sci. 2023;24: pubmed publisher
Wu Z, Person A, Anderson M, Burroughs B, Tatge T, Khatri K, et al. Imaging specific cellular glycan structures using glycosyltransferases via click chemistry. Glycobiology. 2017;: pubmed publisher
Sato K, Takahashi K, Shigemoto Mogami Y, Chujo K, Sekino Y. Glypican 6 Enhances N-Methyl-D-Aspartate Receptor Function in Human-Induced Pluripotent Stem Cell-Derived Neurons. Front Cell Neurosci. 2016;10:259 pubmed
Gao W, Xu Y, Liu J, Ho M. Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain in heparan sulfate. Sci Rep. 2016;6:26245 pubmed publisher
product information
brand :
R&D Systems
master code :
2845-GP
SKU :
2845-GP-050
product name :
Recombinant Human Glypican 6 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human Glypican 6 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Glypican 6 Protein, CF has been validated for the following applications: Binding Activity.
target :
Glypican 6
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
38 kDa and 27-29 kDa, reducing conditions
theoretical molecular weight :
38 kDa and 20 kDa
gene symbol :
GPC6
details of functionality :
Measured by its binding ability in a functional ELISA. When biotinylated recombinant mouse Wnt-3a (25 ng/mL, 100 ╡L/well) is captured on streptavidin-coated plate, Recombinant Human Glypican 6 binds with an apparent Kd 10 nM.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9Y625
applications :
Binding Activity
source :
NS0-derived Recombinant Human Glypican 6 Protein, CF
USD :
541 USD
alt names :
glypican 6, glypican proteoglycan 6, glypican-6, GPC6, MGC126288, OMIMD1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.